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What Are The Side Effects Of Statin?

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Posted on Mon, 27 Apr 2015
Question: I have hereditary very high cholesterol and have been on various statens for many years and now on 40 MG Crestor. I am 70. I've had arthritus on an off and muscle stiffness, but lately arthritus and tendonitus in my hands and forearms has become very debilitating and I am considering stopping the Crestor to see if it is a cause. My VA doctor is a "strictly by the numbers" type so I haven't run this by him yet. Two of my sisters dropped Lipitor for similar reasons and their aches and pains went away. What do you think?
doctor
Answered by Dr. Dr. Naveen Kumar Sharma (1 hour later)
Brief Answer:
Satins causes muscle damages.

Detailed Answer:
Hello,
i have studied your case. You are right in thinking that statin can be cause of your muscle pain and joint pain. So you can stop it for some time after discussing with your doctor.
Other option is that you should get your liver function test and CRP, ESR.If there is muscle damage is there than these tests will be abnormal. If these tests are normal than there can be other causes of joint pin like low calcium and vitmain B12.
I hope this answer helps you. Let me know if there is any other follow up questions.
thanks
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr. Naveen Kumar Sharma (6 hours later)
I have long been aware of the muscle pain side effect. How about statins contributing specifically to arthritus and pain in tendons?

Also a friend just today told me to try CoQ10 to counteract deficiencies caused by statins that result in muscle and joint pain. Would you say that CoQ10 would likely help if I did NOT get off the statins?
doctor
Answered by Dr. Dr. Naveen Kumar Sharma (30 hours later)
Brief Answer:
It is not proven scintifically

Detailed Answer:
Hello,
Statin causes joint pain and tendinopathy but there is no damage to joint cartilage . In your age pain of osteoporosis is also add on. In some patients it can cause destruction of muscles called as Rhbdomyolysis. It is very rare though. So once you stopped it, its effect is reversed. Some patient get benefit from changing to other statins. Also
Co enzyme q is made in body it self. It is part of varrious body metabolism. But it's role in side effect of statin is not proven scinetificlly.
Also it is just a diet supplement and not medicine.
You can take statin( change to other medicine of same group) after discussing with your doctor. Co enzyme q can be added in your diet.
I hope this answer will be helpful for you. Let me know if there is any other followup questions.
thanks
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr. Naveen Kumar Sharma (19 days later)
This is another followup: I have been to see the hand surgeon but I was very disappointed in his lack of communication and negative rapport. He gave me cortizone in both thumb joints and said some thing like: "the only surgery would be to remove the bone [metacarpal I believe] in my thumb since the joint above was destroyed by the arthritis". He also said it would not improve thumb mobility but would reduce the pain. I felt very discouraged. Coincidentally I learned that my neighbor had that bone same removed and some tricks with tendons done and her thumb action was quite normal. I want to know if this is a standard procedure (to do some tendon tricks not mentioned by my surgeon) and whether I could hope for similar thumb performance to my neighbor; or would it be doom and gloom like my hand surgeon made it seem.

The cortizone helps a lot but I expect the improvement will wear off. I am a musician and could not play my guitar until the cortizone. The left thumb and maybe the right thumb need to improve mobility for my music to continue.
doctor
Answered by Dr. Dr. Naveen Kumar Sharma (8 hours later)
Brief Answer:
No surgery for thumb arthritis

Detailed Answer:
Hello,
I have studied your case and your thumb surgeon is right that surgery for thumb arthritis is not a permanent solution and it usually causes relief for short time only. Since basic defect is loss of cartilage in the joint so tendon or bone cutting is not going to help.
As you are saying that cortisone injection has given you good pain relief so I would suggest you to continue with physiotherapy like hot water fomentation, local ointment and mild pain killers.
I hope this answer will be useful for you. Let me know if there is any other followup questions
thanks
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Dr. Naveen Kumar Sharma

Orthopaedic Surgeon, Joint Replacement

Practicing since :2002

Answered : 4486 Questions

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What Are The Side Effects Of Statin?

Brief Answer: Satins causes muscle damages. Detailed Answer: Hello, i have studied your case. You are right in thinking that statin can be cause of your muscle pain and joint pain. So you can stop it for some time after discussing with your doctor. Other option is that you should get your liver function test and CRP, ESR.If there is muscle damage is there than these tests will be abnormal. If these tests are normal than there can be other causes of joint pin like low calcium and vitmain B12. I hope this answer helps you. Let me know if there is any other follow up questions. thanks