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What Are The Repercussions Of Consuming Grapefruit Juice After Taking Plendil?

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Posted on Mon, 21 Sep 2015
Question: Iam takingmPlendil 5mg dauly -- I forgot and drank i/2 small glass of grapefruit juice which I was juicing for friend - juice was watered down.
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Answered by Dr. Vivek Chail (26 minutes later)
Brief Answer:
Please watch for dizziness, increased heart rate or mental confusion

Detailed Answer:
Hi XXXX,
Thanks for writing in to us.

I have read through your query in detail.
Please find my observations below.

1. Plendil contains felodipine which is a calcium channel blocker and helps to control high blood pressure.

2. Grape juice might increase the bioavailability of felodipine and there might be slightly more reduction in blood pressure than usual. However since the juice was watered down, therefore it is less likely to cause any significant observable side effects.

3. Please watch out for any symptoms like dizziness, increased heart rate or mental confusion and if you have any such symptoms then please consult your doctor immediately. In most likelihood, taking half a glass of grape juice which was watered down is not a serious concern.

Please feel free to correct any oversight in my interpretation of your problems and discuss them in detail as per your requirements.

Hope your query is answered.
Do write back if you have any doubts.

Regards,
Dr.Vivek
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Prasad
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Answered by
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Dr. Vivek Chail

Radiologist

Practicing since :2002

Answered : 6874 Questions

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What Are The Repercussions Of Consuming Grapefruit Juice After Taking Plendil?

Brief Answer: Please watch for dizziness, increased heart rate or mental confusion Detailed Answer: Hi XXXX, Thanks for writing in to us. I have read through your query in detail. Please find my observations below. 1. Plendil contains felodipine which is a calcium channel blocker and helps to control high blood pressure. 2. Grape juice might increase the bioavailability of felodipine and there might be slightly more reduction in blood pressure than usual. However since the juice was watered down, therefore it is less likely to cause any significant observable side effects. 3. Please watch out for any symptoms like dizziness, increased heart rate or mental confusion and if you have any such symptoms then please consult your doctor immediately. In most likelihood, taking half a glass of grape juice which was watered down is not a serious concern. Please feel free to correct any oversight in my interpretation of your problems and discuss them in detail as per your requirements. Hope your query is answered. Do write back if you have any doubts. Regards, Dr.Vivek