Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
175 Doctors are Online

Undergone a diagnosis of chronic myelogenous leukemia. Life threatening? Will it come back? Exact cure?

User rating for this question
Very Good
Answered by

Practicing since : 2004
Answered : 1462 Questions
Sir, My Sister XXXXXXX Subramanian has undergone a diagnosis of Chronic Myelogenous Leukemia. I am attaching her report for your reference. I want to know : 1) Is it Life threatening even after going through medication ( currently under 18 months Medication from the U.S)
2) Is it curable fully or will it again generate in the future
3) Wats the exact cure for this , Type of Medicines to be given & the period of Medication.

Currently She is using a new tablet which is the 1 best medicine available for this CML. I am unaware of the name of the same.
Posted Wed, 18 Apr 2012 in Cancer
Answered by Dr. Indranil Ghosh 2 hours later

Thanks for the query.

I have noted the details provided and reviewed the reports.

I feel that the test results are consistent with Chronic Myeloid Leukemia (CML). But I would like to know the 'philadephia chromsome' or PCR for bcr-abl report as well. One of these can confirm the diagnosis of CML.

Probably she is on imatinib (glivec) which is the standard treatment for this condition. She has had a good response so far, as seen on the blood counts and in all probability she will do very well in the future. Currently there is no threat to her life.

However, she needs to continue it lifelong, provided the disease is under control with this medicine. We have to repeat few tests like blood counts, bone marrow cytogenetics and PCR ( polymerase chain reaction) for bcr-abl (blood) time and again to see that she has achieved a complete response and maintaining it.

If at any point, these results show progression of disease, then the drug needs to be changed. There are two other very good drugs availabale, in case need arises.

As of now, this disease is incurable but controllable with medicines. There is 70-80% chance that she will do very well with this drug even after 7-8 years. As Glivec is available for last 10 years only, longer follow-up data is still not available.

Hope this answers your query. I will be available to follow up if you have any other concerns.

Above answer was peer-reviewed by
Share on Facebook
Share on Twitter
Share on Google+
Question is related to
Medical Topics

The user accepted the expert's answer

Ask an Oncologist

© Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions
Already Rated.
Your rating:

Ask a Doctor