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Under-active Thyroid, Pregnant. On Thyroxine. Is An Increased Dosage Harmful?
Question: To: Endocrinologist.I am 5 weeks pregnant and have had an under active thyroid for 12 years. Pre-pregnancy my TSH was 0.98 and i was on 100mcg thyroxine a day. I had a blood test done last week (@ 4weeks pregnant) and my TSH is now 6.68, my doctor has increased the thyroxine by 50mcg, 25mcg when i first found out i was pregnant a week ago and 25mcg today after blood results, so i am now on a dose of 150mcg daily, does this sound correct?
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Hello,
Thank you for posting your query.
I do understand that you have been suffering from an under-active thyroid and on thyroxine replacement, currently pregnant. Your concern seems to be related to the dose of thyroxine.
Your pre-pregnancy TSH (Thyroid Stimulating Hormone) of 0.98 is perfectly fine and a dose of 100mcg is also adequate. In pregnancy, the demand for thyroxine generally increases as the fetus is also initially dependent on maternal thyroxine. Usually the dose of thyroxine is increased by 50mcg during pregnancy.
Your TSH of 6.68 also signifies that the dose is inadequate and I would concur with your Endocrinologist to increase the dose of thyroxine to 150mcg. You can monitor your TSH and maintain your TSH values to less than 2.5 throughout pregnancy. The dose of thyroxine can be titrated as per your TSH values.
Hope I have answered your query. Please accept my answer in case you do not have further queries.
Regards,
Thank you for posting your query.
I do understand that you have been suffering from an under-active thyroid and on thyroxine replacement, currently pregnant. Your concern seems to be related to the dose of thyroxine.
Your pre-pregnancy TSH (Thyroid Stimulating Hormone) of 0.98 is perfectly fine and a dose of 100mcg is also adequate. In pregnancy, the demand for thyroxine generally increases as the fetus is also initially dependent on maternal thyroxine. Usually the dose of thyroxine is increased by 50mcg during pregnancy.
Your TSH of 6.68 also signifies that the dose is inadequate and I would concur with your Endocrinologist to increase the dose of thyroxine to 150mcg. You can monitor your TSH and maintain your TSH values to less than 2.5 throughout pregnancy. The dose of thyroxine can be titrated as per your TSH values.
Hope I have answered your query. Please accept my answer in case you do not have further queries.
Regards,
Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.
Above answer was peer-reviewed by :
Dr. Shanthi.E
Answered by
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