Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
140 Doctors are Online

Tested negative for HBsAG but reactive for core antibodies for hep b. What are the risk to unborn?

User rating for this question
Very Good
Answered by

General & Family Physician
Practicing since : 2009
Answered : 3094 Questions
i tested negative for HBsAG but reactive for core antibodies for hep b since i had been exposed to hep b when i was a child. i recently delivered twins and want to know what this means for them. they did not receive hep b vaccines yet since i was misinformed about my test results. i was tested for HBsAG while i was pregnant but not for HBcAB. I only recently found out about my reactive test results due to blood tests that were done for cord blood registry. should i be concerned that i may have exposed my newborn twins to hep b?
Posted Mon, 1 Apr 2013 in Infections
Answered by Dr. Luchuo Engelbert Bain 19 minutes later
Hi and thanks for the query,
Interpretation of HBcAB positive result with negative HBsAG is clinically difficult and is often not done. The presence of HBcAB simply means you have come in contact with the virus sometime in the past. Is it completely cleared off or does the virus still exist? With negative HBsAG, an answer cannot be given. Your children could really need be vaccinated. Generally, vaccination is based in HBsAG positivity. The practice differs from centre to centre, but I suggest you get advice from a gastroenterologist.
Repeating the tests for HBcAB and HBsAG could be wothwhile. If the results still stand out same with HBsAG being negative, and HBcAB being positive, you get the children vaccinated.
But as far as you are concerned, you are ok provided the HAsAG results remain negative.
Thanks and best regards,
Do not hesitate asking further questions and consulting your gastroenterologist for test reconfirmation could be comforting. You need not worry.
Luchuo, MD.
Above answer was peer-reviewed by
Follow-up: Tested negative for HBsAG but reactive for core antibodies for hep b. What are the risk to unborn? 42 hours later
can i give my twins hep b since i have core antibodies to hep b from a past exposure? wondering if there might be a chance of infection during labor and delivery; i had a c-section
Answered by Dr. Luchuo Engelbert Bain 18 minutes later
Hi and thanks for the query,
In my humble opinion, if you do another control test and you are still HBsAG negative and HBcAB positive, you can go ahead and vaccinate the children.
Thanks and best regards,
But an appointment with your gastroenterologist is very welcome.
Nice day,
Luchuo, MD. Feel free asking further questions if need be,
Above answer was peer-reviewed by
Share on Facebook
Share on Twitter
Share on Google+
Question is related to
Diseases and Conditions
Medical Procedures

The user accepted the expert's answer

Ask an Internal Med Specialist

© Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions
Already Rated.
Your rating:

Ask a Doctor