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Taking high dose of thyronorm for hypothyroid. Gaining weight, having irregular period. Normal?

Sep 2012
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General & Family Physician
Practicing since : 2008
Answered : 1416 Questions
My friend has hypothyroid and recently increased medication of thyronorm from 75 mg to 100 mg. She has putup around 3 kgs and also she has irregular periods. Is it normal? Not sure what to do further. please suggest.
Posted Sat, 13 Apr 2013 in Thyroid Problem and Hormonal Problems
Answered by Dr. Das Arindam 27 minutes later

Thank you for posting here.

Look, in hypothyroidism, patient has to take the thyroxine supplement for rest of her life. The dose of the supplement should be adjusted according to the thyroid profile status. So, she has to do thyroid profile test every 6 months.

Now, in this age group, patients have a tendency to develop multiple hormonal problems besides having hypothyroidism. Most common is polycystic ovarian syndrome (PCOS). In this condition, irregular periods and increased weight, are very common.

So, she has to do a total hormonal profile assay including LH, FSH, prolactin, estrogen and progesterone levels. An ultrasound scan of whole abdomen is necessary to exclude the possibility of PCOS.

In case of PCOS, you have to take oral contraceptive pills to regularize the period. Besides, you have to take metformin group of drug also.

So, tell her to consult a gynecologist immediately for a clinical examination and for ordering necessary investigations and also for further management accordingly.

Hope this information suffices. Let me know if you have any more question.

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