Taken overdose of Larezapen for sleeplessness. Not responding. What to do?

default
Posted on Fri, 22 Jun 2012 in Sleep Disorders
Question: iv tried every thing under the book n nothing seems to b working , I went to my dr today n he gave me larezapen 1mg he said take two but if nothing take 3 , iv took 6 n I'm still up at 2pm the morning , I'm so frustrated !!!!!
doctor
Answered by Dr. Hema Yadav 50 minutes later
Hello,

Thanks for posting your query.

Lorazepam is a sedative which may take 90 to 120 minutes to start action after oral ingestion and higher than prescribed dose can lead to toxic symptoms. Usually not more than 10 mg in divided dose is prescribed. Please do not take more than recommended dose as it can cause serious side effects and sometimes is lethal (10 gm/kg).

In your case you might have experienced “paradoxical effects” caused by more than required dose.

In some cases, there can be paradoxical effects with benzodiazepines, such as increased hostility, aggression, angry outbursts, and psychomotor agitation. These effects are seen as more common with lorazepam than other benzodiazepines.

Paradoxical effects are more likely to occur with higher doses, in patients with pre-existing personality disorders and those with a psychiatric illness. It is worth noting that frustrating stimuli may trigger such reactions, even though the drug may have been prescribed to help the patient cope with such stress and frustration in the first place.

As paradoxical effects appear to be dose-related, they usually subside on dose reduction or on complete withdrawal of lorazepam.

Kindly consult your doctor for a change of dose or alternative anxiolytic like xanax. And please do not take any more than prescribed dosage to prevent life threatening complications.

Hope I have answered your query. Should you have any additional concerns, I will be available to address them.

Regards

Above answer was peer-reviewed by : Dr. Prasad
doctor
Answered by
Dr.
Dr. Hema Yadav

Pediatrician, Infectious Diseases

Practicing since :2005

Answered : 1528 Questions

premium_optimized

The User accepted the expert's answer

Share on
Question is related to
Diseases and Conditions
Drug/Medication ,   ,   ,  
Medical Topics

Recent questions on  Beta-lactam

doctor1 MD

Ha left side and top of head. Sometimes behind eye left mostly. Do see shiny metallic like spots occassionally Have felt shock like feeling (mainly...

doctor1 MD

Hi there,

I have ED and have been on viagra for 10+ years. From time to time , once in a blue moon I will take one and not able to maintain an...

doctor1 MD

hi i had taken valparin chrono tablets (300 mg in morning & 500 mg at night) for 4 yrs ...for the treatment of neurocysticercosis..now as adviced...

doctor1 MD

69 yr old male,stent to rca in 2009. echo normal with ejection rate of 55-60.B P130/80.wt. 61 kg, ht. 5'6'.no sugar problem.Can I use tadalafil? I...

doctor1 MD

If I took to many alprozlam could it kill me?

doctor1 MD

pristiq desvenlafaxine 100 mg and sandomigran 500 mcg what side effects can there be

doctor1 MD

Can halcion after long term use cause temporary lack of coordination and dizziness? I take .5mg per night.Never had these reactions before.

Get personalised answers from verified doctor in minutes across 80+ specialties

127 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
backtotop2