Brief Answer: Migraine can be controlled by prophylactic drugs. Detailed Answer: Hello Welcome to health care magic and thank you for writing to Health care magic It seems from the history that your partner is on treatment with Simponi for treatment of ankylosing arthritis. He is also suffering from migraine headache. Headache is one of the common side effect of the Simponi, a drug which acts to reduce inflammation in the body. Simponi is commonly used in treatment of chronic inflammations like ankylosing arthritis. The other side effects of the drug are cough, muscle pains, body aches, blurring of vision, tiredness, breathing difficulties..., if you any of these symptoms along with headache you need to consult your doctor for change of the drug. If you are having true migraine headache the treatment options are using analgesic drugs like paracetamol in acute phase. Since you are having recurrent attacks of migraine, you need to take prophylactic drugs to prevent recurrent attacks of migraine. The commonly used prophylactic drugs are flunarizine or beta blockers like propranolol. Hence I advice you to consult your doctor for confirmation of diagnosis that the problem your partner is having is migraine only and not related to the Simponi drug and for prescription of the prophylactic drugs like flunarizine or propranolol for prevention of recurrent attacks of migraine. Hope the information is helpful to you. Thank you

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