Question: So, over the past 5 years I have a reoccurring condition of feeling poisoned! I have just had another bout of this 48 hr. condition, probably 7-9 occurrences over this time period, and a couple have occurred nearly at similar times of the calendar year. Symptoms... initial discomfort in stomach, then distended stomach, then severe discomfort for the next 12-20 hours, primarily abdominal, but not isolated to a particular area of the stomach. This on a couple occasions has led to vomiting which only brings bile. Severe sweating, over the duration of the condition. Condition ALWAYS subsides within 48 hrs almost like clockwork, The condition brings flu like symptoms, body aches along with the discomfort of a severe hangover! I have had medical blood tests to no avail, including ultra-sound of gall bladder, all revealing nothing abnormal. Urine is dark on second day and very bubbly on second and third day (like I poured dish soap into the toilet!). I have a suspicion at this point that I might have a mushroom intolerance condition, as this has been one of the foods common to the occurrence (except this last bout), I have eliminated mushrooms from my diet altogether and have missed a couple of these occurrences that seemed to be common to the calendar. Ideas? If this is a histamine release issue is there some neutralizing agent that I might try to isolate it or to rule something out. I did have a couple mushrooms one eve, (only 2) and did have a mild occurrence, so I am very suspicious. Need a solution to kill this in advance of it making me so sick and lying horizontal for 24 hours of hell! Thanks!

Great...Thanks for the response. I have not had any allergy testing done to date. Elimination of mushrooms has seemed to helped, although I have no direct understanding of this recent bout, as no mushrooms were eaten to my knowledge, also, from my reading there may be a time delay associated with my body's reaction, so when I got exposed (if this is the issue) makes this more of a mystery. Question... so, when or how long would the active agent remain in my stool or blood for these tests? Would I have to be having the condition for the test to determine the specific allergen? I really would hate to have to suffer thru another bout of this but it might be worth it to eat a couple mushrooms to fully understand why my body reacts so violently to whatever is poisoning me and to never have this reoccur. Thanks for your input. One more thing... Is there a specific over the counter antihistamine like Benadryl that you might recommend in the event of a re-occurrence or to minimize it's impact? Thanks much for your time and interaction. Best regards, XXXXXXX

Dr. Bhavsar,

two questions...

1. How long would the violating protein remain in my blood or stool after an occurrence to be detected by these tests.

2. Is there a specific over the counter antihistamine like Benadryl that you might recommend in the event of a re-occurrence or to minimize it's impact?

Thanks...

Thanks...

My weight is 196 US lbs

Thanks for the positive interaction... appreciate the information! XXXXXXX