HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

question-icon

Suggest Treatment For Recurrent Pancreatic Adenocarcinoma

default
Posted on Mon, 1 Jun 2015
Question: Sir,
Recurrence pancreatic adenocarcinoma.
Ca 19 9 levels -250.
Celiac lymph nodes metases.
On pet scan.no cancer anywhere else.
Doc advised folfirinox. 3 cycles.
Followed by radiation.
Liver function test -normal.

Doctor said localised recurrence.
Please suggest prognosis. XXXXXXX Makharia.
doctor
Answered by Dr. Indranil Ghosh (30 minutes later)
Brief Answer:
yes folfirinox is a suitable regime

Detailed Answer:
Hi
Thanks for your query.

It is a difficult scenario. Surgery unlikely to help. Hence chemotherapy with folfirinox is the treatment of choice. It has the highest response rates.

If there is a good response, radiation can be considered.

Now the unfortunate part is that even though localized recurrence, it is not curable. We can however try controlling it as long as possible.

Hope this helps. I will be available for follow up.
Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Indranil Ghosh (2 minutes later)
life expectancy.
doctor
Answered by Dr. Indranil Ghosh (19 minutes later)
Brief Answer:
difficult to predict

Detailed Answer:
From my past experience I can say 1-2 years maybe.

However it is not possible to predict in an individual patient
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Indranil Ghosh (10 minutes later)
Sir
there are 2 lymph nodes measuring 1.4 cm and 1 cm.
in my case life expectancy and progression free survival
doctor
Answered by Dr. Indranil Ghosh (58 minutes later)
Brief Answer:
disease burden low so it may be more

Detailed Answer:
But still the average progression free survival with FOLFIRINOX is about 6-12 months and life expectancy 1-2 years. In any individual case very difficult to predict. Some patients may even survive 5 years but that is a small proportion.

Note: For further queries related to kidney problems Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Indranil Ghosh

Oncologist

Practicing since :2004

Answered : 1712 Questions

premium_optimized

The User accepted the expert's answer

Share on

Get personalised answers from verified doctor in minutes across 80+ specialties

159 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
Suggest Treatment For Recurrent Pancreatic Adenocarcinoma

Brief Answer: yes folfirinox is a suitable regime Detailed Answer: Hi Thanks for your query. It is a difficult scenario. Surgery unlikely to help. Hence chemotherapy with folfirinox is the treatment of choice. It has the highest response rates. If there is a good response, radiation can be considered. Now the unfortunate part is that even though localized recurrence, it is not curable. We can however try controlling it as long as possible. Hope this helps. I will be available for follow up. Regards