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Suggest treatment for psoriasis and psoriatic arthritis

Answered by
Dr. Kakkar S.


Practicing since :2002

Answered : 8168 Questions

Posted on Wed, 30 May 2018 in Skin Hair and Nails
Question: My husband has psoriasis and psoriatic arthritis. He takes methotrexate, which has been effective. His PCP and our pharmacist have told him he needs to be off the methotrexate for a period of time, if he wants to receive the shingles vaccination. His rheumatolagist disagrees. Any information would be helpful.
Answered by Dr. Kakkar S. 38 minutes later
Brief Answer:
Live vaccines should be avoided while on methotrexate

Detailed Answer:
Hello. Thank you.
I am Dr kakkar (Dermatologist and Venereologist). I have noted your concern.

Shingles vaccine is a live attenuated vaccine. So anybody with a weakened immune system or on immunosuppressives is at risk of developing disseminated disease with the live virus. Since methotrexate is an immunosuppressive so he should not receive this vaccine while on methotrexate.

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