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Suggest Treatment For Pituitary Adenoma With Growth Hormone

Posted on Mon, 23 Mar 2015

Question: Sir, I was diagnosed as pituitary adenoma with growth hormone producing 3yrs ago for which they have done surgery twice with a gap of 2 years and then followed by radiation as it was reoccurring. After 1st surgery I was given wysolone 5mg for 6 months. My weight increased for 52 to 65. After 2 surgery I lost my periods so they gave me progynova plus meprate after which I increased form 65 to 80. Now they shifted me to femilon even after rigours excrecise and diet I'm not putting down wt. My doctor days says it may be due to excessive growth hormone that is realesing from the adenoma so I'm taking octerotide inj. Also but their is no decreasing in my weight can u tell me the actual reason of my weight gain and the best way to loss it as I tried all possible ways. Thank you

Answered by Dr. Ajish TP (1 hour later)

Brief Answer:
It could be due to GH, steroids, HRT

Detailed Answer:
Hi XXXX,

Welcome to HCM. I have gone through the question and understand your concerns.

There are multiple reasons for your weight gain. Growth hormone will increase the weight if it is not controlled with octreotide. Hormone replacement treatment - progynova, meprate and wysolone are having weight gain as side effects.

Please check your blood sugars are you are at risk of diabetes, which is also associated with weight gain.

Hope I have answered your questions. If you have any further queries I will be happy to help you.

Regards,

Dr Ajish TP [MD,DM]
Consultant Endocrinologist

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Ajish TP (27 minutes later)

OK thank you sir. Then what would be the best way to reduce this type of weight. And I'm unmarried now. So what is method used for me to get pregnancy

Answered by Dr. Ajish TP (4 hours later)

Brief Answer:
Diet and exercise, LH,FSH treatment

Detailed Answer:
Hi XXXX,

Welcome back.

A. Weight reduction

For any type of weight gain, there are only 3 options:
1. Diet and exercise
2. Weight reducing medications - like oralistat and lorcaserin.
3. Surgical treatment - bariatric surgery

In your situation medications or surgical treatment is usually not preferred as an initial treatment. So we should stick with diet and exercise.

Frequent small feeds high in fibre- 3 meals and 4 low calorie snacks is the key. Do regular aerobic exercise 30 minutes a day.

B. Pregnancy

Pituitary hormones are needed for ovulation and regular menstruation. Here you lack LH and FSH.LH/FSH injections are available. You can have pregnany with help of these injections.

Wishing you good health.

Regards
Dr Ajish TP

Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar