Suggest Treatment For Multiple Myeloma And Dermamysotosis
You need more work-up!
Detailed Answer:
Hi! thanks for your health query!
From your description, I would summarize that you have monoclonal protein in urine, high CRP, low blood proteins and severe anemia, in addition to the diagnosis of dermatomyositis!
I would say that you are correct as there is strong possibility of multiple myeloma; please follow my suggestions as below if they appear reasonable to you:
1. have a serum protein electrophoresis and immunofixation, complete hemogram, serum calcium level, b2-microglobulin level and x-ray/CT scan of your pelvic/spinal bones
2. please mention the details of the biopsy report that reads 'dermatomyositis' along with ANA titre and also mention if any specific problem with your facial skin, neck region movements etc..
No or hardly any relation to HIV; just forget it! They must have done it due to an error. Good that they apologized for that error. In HIV neg documented people it is not required to go for such test.
Welcome you with feedback!
Regards
Thank you for your feedback. The have just recently begun the CT's and MRI's. The other blood work has come in normal, but I will copy and paste here for you to see. I also had pneumonia in 09 (4 different antibiotic before cleared) and double pneumonia in 2011 (a bit more resistant, but cleared). I now get a vaccine every 5 years and take my vit D, as it was low (now normal at 50, but I take 6-8 thousand IU's daily to maintain this level. I recently read a journal article noting Vit D and some kind of exacerbation of Multiple Myeloma. Have you heard of this? One other question regarding the C reactive protein and Monoclonal development, I read another journal article that stated during treatment of Multiple Myeloma the c reactive protein actually enhances proliferation of monoclonal development (non-scientific terms as I am paraphrasing here). If that is the case, what would be the best course of Tx since both of these numbers are high according to my blood work? Again, thank you for your time and consideration. I will post all blood work later today.
I can also cite the journal articles if you like.
CRP is non-specific ; please don't give much importance!
Detailed Answer:
Hi! CRP is rapidly replacing ESR as a prognostic marker of any kind of inflammation/infection/malignancy and your value is not that much raised; please don't give much importance to it!
Vitamin-D deficiency has a negative impact on Multiple Myeloma. but please don't give much importance to this as they may just co-exist also without any significant effects...
Only immunofixation, protein electrophoresis, imaging and plasma cell percentage in the bone marrow could confirm a diagnosis of multiple myeloma....!
Please share all detailed reports then..
regards,