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Suggest Treatment For Minimally Invasive Follicular Carcinoma

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Posted on Mon, 14 Apr 2014
Question: Hi Dr. my age is 30 years. I had goiter for last 5 years on my left thyriod. It was year 2007 when goiter find and grow very sloely. i was on Homeopathic medicine but not cured. In the mean time my goiter grow, Then I decide for surgery. Following sequences are: 23/09/2013 FNAC done and result "suggestive of adenomatous nodules. 27/09/2013 CT Scan done and result "A large (73mm*61mm size) well defined heterogeneous density nodule is seen in the left lobe thyriod." 4/10/2013 thyriod scan is done and result "cold nodule involving nearly the entire left". 26/10/2013 surgery done hemi thyroidectomy left side, and after surgery, Biopsy report "features are suggestive of minimally invasive follicular carcinoma, thyriod with focal hurthle cell change and tumor 250grm. 16/11/2013 again second operation of total thyroidectomy. Biopsy report " NO evidence of follicular carcinoma is seen." ..........then my surgen advice me for radioactive iodine. I was gone cancer hospital in KOLKATA for radioactive iodine. Here my I-131 scan done and was find that "neck uptake (48 hrs.) =7.7% i.e. 7.7% thyriod cell are still functioning. Then cancer hospital dr. advice me for third operation for removal of 7.7% functioning thyriod cell and then radioactive iodine. What should I do. Is third surgery is necessary. I am in confused mind. please help me?
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Answered by Dr. Shailja Puri (2 hours later)
Brief Answer: Third surgery is necessary. Refer to answer below Detailed Answer: Hello, Thanks for posting your query on HealthCareMagic. The history given by you tells that you had a minimally follicular carcinoma in the left lobe of the thyroid. The management of minimally invasive follicular carcinoma is total thyroidectomy. In the first surgery, one one lobe was removed since the fine needle aspiration reported it as adenomatous nodule. Sometimes, exact diagnosis cannot be made on FNAC because it solely depends on the cells sampled. FNAC is a blind procedure so the cancerous cells could have been missed on it. After the first surgery, the lesion turned out to be a cancer, thus necessating total thyroidectomy. After total thyroidectomy a radioactive iodine uptake was done. Radioactive iodine is picked up by functioning thyroid cells and not by other tissue since thyroid cells are rich in iodine. The radio active iodine uptake showed presence of thyroid cells, thus showing that some residual thyroid tissue is still present which may develop cancer at later stage. Thus, this third surgery is necessary and radio active iodine uptake needs to be repeated to check the completeness of the surgery. Kindly, be patient. The treatment is for your benefit. If you have more queries, I will be glad to answer. Dr Shailja P Wahal
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Above answer was peer-reviewed by : Dr. Raju A.T
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Dr. Shailja Puri

Pathologist and Microbiologist

Practicing since :2006

Answered : 9705 Questions

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Suggest Treatment For Minimally Invasive Follicular Carcinoma

Brief Answer: Third surgery is necessary. Refer to answer below Detailed Answer: Hello, Thanks for posting your query on HealthCareMagic. The history given by you tells that you had a minimally follicular carcinoma in the left lobe of the thyroid. The management of minimally invasive follicular carcinoma is total thyroidectomy. In the first surgery, one one lobe was removed since the fine needle aspiration reported it as adenomatous nodule. Sometimes, exact diagnosis cannot be made on FNAC because it solely depends on the cells sampled. FNAC is a blind procedure so the cancerous cells could have been missed on it. After the first surgery, the lesion turned out to be a cancer, thus necessating total thyroidectomy. After total thyroidectomy a radioactive iodine uptake was done. Radioactive iodine is picked up by functioning thyroid cells and not by other tissue since thyroid cells are rich in iodine. The radio active iodine uptake showed presence of thyroid cells, thus showing that some residual thyroid tissue is still present which may develop cancer at later stage. Thus, this third surgery is necessary and radio active iodine uptake needs to be repeated to check the completeness of the surgery. Kindly, be patient. The treatment is for your benefit. If you have more queries, I will be glad to answer. Dr Shailja P Wahal