Suggest treatment for low Apgar scores and respiratory distress in infants
Thanks for writing to us with your health concern.
I am Dr. Abraham, OB - GYN, and would be glad to assist you with your concern.
Low PAPPA - A is generally a screening test done to screen babies at high risk of Down's syndrome.
A positive screen ( low PAPP - A ) prompts further evaluation for Down's syndrome.
Recently, there is evidence to show that a low PAPPA level is associated with other adverse perinatal outcomes such as -
small size for gestational age (SGA), preterm labour, hypertensive disorders of pregnancy, spontaneous abortion, and stillbirth.
Most of these conditions would result in a baby born with low Apgar scores and respiratory distress.
Yes, a low PAPPA level should alert the obstetrician regarding a higher risk for development of such factors.
Follow up testing is recommended in such a case, particularly if the mother has any ominous features in history, physical exam or family history.
I would be most happy to elucidate further if you could elaborate on what you specifically wish to discuss here.
Hope my answer helped you.
All the best
Please feel free to discuss further.
Please go through the links.
Sorry for a delay in the response, was somehow unable to access the internet !
I have read your follow up, and first of all, thank you for your appreciative, kind words.
You help us to keep doing our work !
Now for your question.
IT is quite consistent with the website policy for me to provide you with relevant studies or medical literature that you might ask for.
In this case, we are looking for studies that indicate that a low PAPP- A in the first trimester can lead to respiratory distress, low Apgar scores and apnea at birth.
I am providing a few links, kindly peruse them, and let me know if I can help in any further manner.
Here are the links -
https://fetalmedicine.org/abstracts/2014/abstracts/522.pdf ( Read the conclusion particularly in this article - it pertinently answers your index query )
I have posted 4 studies.
I hope that should suffice.
Take care, and looking forward to hearing from you.
The User accepted the expert's answer
Get personalised answers from verified doctor in minutes across 80+ specialties
- Treatment and cure for acute respiratory distress
- Treatment and cure for Acute respiratory distress syndrome
- Treatment and cure for neonatal respiratory distress
- Treatment and cure for Respiratory distress
- Drugs/medication for Infant respiratory distress syndrome
- Diagnosis of Infant respiratory distress syndrome
- Treatment and cure for respiratory distress syndrome
- Treatment and cure for Infant respiratory distress syndrome
- Infant respiratory distress syndrome causes
- Symptoms of Infant respiratory distress syndrome