question-icon

Suggest Treatment For Invasive Lobular Carcinoma

default
Posted on Mon, 5 Jan 2015
Question: My daughter was recently diagnosed with breast cancer. She said that the doctors changed their diagnosis for invasive ductal carcinoma to invasive lobular carcinoma and it is ER/PR positive and HER 2 negative. Could you please provide further definition/descriptions of her condition.
doctor
Answered by Dr. Grzegorz Stanko (30 minutes later)
Brief Answer:
This is a very good result.

Detailed Answer:
Hello!

Thank you for the query.

First and most information about her cancer is in what sage it has been detected. Stage of the cancer can be established when we know: tumor size, lymph nodes state (if there are any metastases in armpit lymph nodes) and if there are any metastases to other parts of the body.
Stage of the cancer is what gives the information about how advanced is the disease and what survival rate should she expect. For example, breast cancer limited to the breast only (no metastases in lymph nodes) and smaller than 2 cm is stage I. Breast cancer with no more than 3 regional lymph nodes metastases is stage II.

Invasive lobular carcinoma described the histological type of the cancer. It means that the cancer descents from milk-producing lobules of the breast. In contrast, invasive ductal carcinoma means that the cancer starts from milk ducts. For your daughter histological type does not make much difference with treatment or survival rate.

First of all few words about what receptor is. Receptor is a protein on the surface of the single cell. Lets call this protein a lock. Now every receptor can react to a specific protein (the protein connects with the receptor and sends signal inside the cell). This protein is a key. So receptor is a lock which can be open with a key (another protein).

ER/PR positive means that the cancer cell has on its surface receptors for estrogen and progesterone. This is very good information. This receptors gives the possibility to impact on cancer cells with antiestrogen medicine called Tamoxifenum. In simple words we have medicine which will prevent cancer cells from regrowing/giving metastases etc.
HER 2 negative is also very very good news. HER 2 is a special receptor for growing factor. If the cancer cell contains too much of this receptor, it multiply very fast. If the cancer multiply very fast, the cancer is aggressive.

In your daughter result also cancer cells grade is missing (it is marked with G and a number - G1, G2, G3). This also gives information about how aggressive is the tumor.

Hope this will help. Feel free to ask further questions.
Regards.
Above answer was peer-reviewed by : Dr. Raju A.T
doctor
Answered by
Dr.
Dr. Grzegorz Stanko

General Surgeon

Practicing since :2008

Answered : 5774 Questions

premium_optimized

The User accepted the expert's answer

Share on

Get personalised answers from verified doctor in minutes across 80+ specialties

152 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
Suggest Treatment For Invasive Lobular Carcinoma

Brief Answer: This is a very good result. Detailed Answer: Hello! Thank you for the query. First and most information about her cancer is in what sage it has been detected. Stage of the cancer can be established when we know: tumor size, lymph nodes state (if there are any metastases in armpit lymph nodes) and if there are any metastases to other parts of the body. Stage of the cancer is what gives the information about how advanced is the disease and what survival rate should she expect. For example, breast cancer limited to the breast only (no metastases in lymph nodes) and smaller than 2 cm is stage I. Breast cancer with no more than 3 regional lymph nodes metastases is stage II. Invasive lobular carcinoma described the histological type of the cancer. It means that the cancer descents from milk-producing lobules of the breast. In contrast, invasive ductal carcinoma means that the cancer starts from milk ducts. For your daughter histological type does not make much difference with treatment or survival rate. First of all few words about what receptor is. Receptor is a protein on the surface of the single cell. Lets call this protein a lock. Now every receptor can react to a specific protein (the protein connects with the receptor and sends signal inside the cell). This protein is a key. So receptor is a lock which can be open with a key (another protein). ER/PR positive means that the cancer cell has on its surface receptors for estrogen and progesterone. This is very good information. This receptors gives the possibility to impact on cancer cells with antiestrogen medicine called Tamoxifenum. In simple words we have medicine which will prevent cancer cells from regrowing/giving metastases etc. HER 2 negative is also very very good news. HER 2 is a special receptor for growing factor. If the cancer cell contains too much of this receptor, it multiply very fast. If the cancer multiply very fast, the cancer is aggressive. In your daughter result also cancer cells grade is missing (it is marked with G and a number - G1, G2, G3). This also gives information about how aggressive is the tumor. Hope this will help. Feel free to ask further questions. Regards.