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Suggest Treatment For Infertility Problem

Posted on Thu, 16 Oct 2014

Question: My sister went thru 3 IVF cycle & all the 3 cycle got failed . First Cycle failed reason - Endo wall was thick . Second Failure reason - No reason so for the next cycle Hystro was suggested . Third Cycle - Hystro Done / 5 Embryos of grade 2 were transfered .Then also cycle failed . She did all the cycles with her own eggs . What do you think went wrong .? Please advice !! What should she do ? Please tell me something about surrogacy ? How much would it cost ? Where is the best & economical surrogacy done ? Her uterus is fne . She is so depressed now & have lost all hopes . Since , it is said if 3 cycles failed & reason is unknown then chances are very less . After hystro , it was said that scraping and all done , she would conceive . Everytimes 5 embryos were transfered and ty dont get planted .

Answered by Dr. Mahesh Koregol (19 minutes later)

Brief Answer:
details

Detailed Answer:
Hi

I read your query and I understand your concerns.

I need few details before answering your question.

1. How many eggs were retrieved each cycle and how many mature eggs.

2. If you have IVF summary of each cycle please scan and upload.

3. Out of each cycke how many embryos and what was grade.

4. How is semen analysis report of husband.

5. Where were all these IVF cycles done. Which centre.

Please provide above details which will help me to answer your query in detail.

Regards

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Mahesh Koregol (5 minutes later)

Each cycle almost 9 to 10 eggs were retrieved & 6 matured - So everytime 5 embryos were transferred. This time egg quality - Grade 2 & last 2 times it was much better as per docter .
Seimen analysis report was absolutely fine .
Treatment done - XXXXXXX XXXXXXX -Bengali Market -Very famous XXXXXXX IVF Centre

Answered by Dr. Mahesh Koregol (1 hour later)

Brief Answer:
PGD / Donor

Detailed Answer:
Hi,

Since her is 36 years and she has failed 3 cycles already the time is to go ahead with next step.

The next step would be IVF using donor eggs. If she is insisting on her own eggs, better to go for PGD ( Preimplantation genetic diagnosis) before embryo transfer.

Regards

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Mahesh Koregol (4 minutes later)

what is PGD ? Chances are better with donor eggs?? have asked you about surrogacy and from where to get this done ??With Donor eggs, no resemblence on mother right ??

Answered by Dr. Mahesh Koregol (28 minutes later)

Brief Answer:
Details

Detailed Answer:
Hi,

1. Donor eggs are from a different lady and nothing to do with your sister. There wont be resemblence to mother ( your sister) as there are no genes from her and no role of her.

2. PGD ( Preimplantation genetic diagnosis ) is a process where in embryo biopsy is done and subjected for diagnosis of chromosomal abnormalities.

3. Only best embryos which are reported normal are transferred after the PGD.

4. Surrogacy is a process where embryo are placed in a different women instead of your sister's uterus. This does not seem to be necessary at this stage.

5. Chances are better with donor eggs in your sister's case.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Mahesh Koregol (5 minutes later)

but when planting issue is there then how come with donor eggs , success chances are there ?? Coz, she is producing her own eggs as well . Do you think accu pressure also helps .Still can you advice clinics in XXXXXXX . Which is economical & best .

Answered by Dr. Mahesh Koregol (21 minutes later)

Brief Answer: XXXXXXX

Detailed Answer:
Hi,

Since she is 36 years old, her eggs will not be of good quality. She might be producing eggs but of inferior quality. Hence undergoing repeated failure.

Donor eggs if taken from a young lady has better chances.

In XXXXXXX You can meet IVF Specialist Dr. XXXXXXX XXXXXXX XXXXXXX no. 0000. She will be best person to guide you and give you best options in XXXXXXX Quote my name as reference when you call her.

Regards,
Dr. Mahesh Koregol
IVF & Infertility Specialist

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Mahesh Koregol (5 minutes later)

Thanks!

grade 2 are poor quality eggs . if egg quality is good then there wont b ny plantation issue ?

Answered by Dr. Mahesh Koregol (4 minutes later)

Brief Answer:
Yes

Detailed Answer:
Hi,

Grade 2 are poor embryos.

Embryos if are good quality the chances of successful pregnancy are high. The implantation issues are less in such cases.

But in IVF 100 percent implantation can never be promised.

Regards

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar