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Suggest Treatment For Elevated Liver Enzymes And Kidney Stones

Posted on Thu, 13 Nov 2014

Question: Recently have communicated with a few doctors here on the site. Have many symptoms. Some probably due to perimenopause. But some I am wondering if correlate to the parathyroid gland. I also have many kidney stones in my left kidney. I also have a male cousin who is experiencing many of the same I have. Started doing a little research about our family history. About 75% have had kidney stones(calcium) about the same percent have skeletal deformities.(scoliosis or kyphosis) myself have kyphosis. Large percent have had gallstones and ended up having gallbladder removed. large number have had dentures at very young ages. such as 16 and 29. due to weak tooth enamel. Myself have weak tooth enamel and have dental work done about every 6 months. Most of the people with the stones and deformities have developed heart problems as they age. arrhythmias and heart attacks. Both my cousin(male) also have elevated liver enzymes. I have had my calcium checked in past was 9.6. Does this sound like an inherited parathyroid problem? can your calcium levels fluctuate?

Answered by Dr. Shehzad Topiwala (21 minutes later)

Brief Answer:
Yes

Detailed Answer:
Calcium levels can fluctuate but that is usually related to meals. For example, they can rise temporarily after a meal, and normalize soon thereafter.
In some calcium disorders, blood calcium levels can fluctuate over time and therefore periodic retesting maybe necessary.

There is an inheritable condition called "Familial Hypocalciuric Hypercalcemia' in which calcium and Parathyroid hormone levels in the blood are mildly elevated. Interestingly, this condition is benign and does not require treatment.

You must have had some routine labs done, such as
CBC
CMP
TSH
Free T4

When I see someone like you in my practice I also order a blood test for 25 hydroxy vitamin D. This does not require fasting.

A nephrologist will help you determine the cause of your kidney stones.

If you have lost height and broken bones easily, a DXA Bone density test is in order

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Shehzad Topiwala (37 minutes later)

could a overactive parathyroid also cause muscle tension and weakness? dizziness? and elevated liver enzymes? will request 25 hydroxyl vitamin d. tsh was tested it was .66 and free t4 was 1.0. what is the CMP labs?

Answered by Dr. Shehzad Topiwala (1 hour later)

Brief Answer:
Follow up

Detailed Answer:
1 Yes. Overactive parathyroid glands have been associated with muscle/bone related symptoms

Not so much so with dizziness though.

Not with elevated liver enzymes either.

2 CMP includes
Electrolytes
Calcium
Glucose
Liver function tests
Kidney function tests

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Shehzad Topiwala (43 minutes later)

should the thyroid also be retested occasionally? thanks

creatine was also low.

Answered by Dr. Shehzad Topiwala (11 hours later)

Brief Answer:
Third follow up

Detailed Answer:
Whether or not the thyroid should be retested occasionally is a decision made by your endocrinologist who will need to examine you periodically. The same applies to low creatinine......whether or not it is of relevance in your circumstance depends on a detailed physical examination. Generally a low creatinine is not a problem in a seemingly well individual. However it is also low in those with protein malnutrition and those with muscle loss.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Shehzad Topiwala (9 hours later)

Recently have been taking a calcium, magnesium, and zinc supplement. should that be discontinued until I can get the above tests done?

Answered by Dr. Shehzad Topiwala (33 minutes later)

Brief Answer:
Yes

Detailed Answer:
Yes it is advisable to do so and resume after the sample is taken. Then discuss the results with your endocrinologist and see which ones you need to continue, if any

Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar