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Suggest treatment for child nephrotic syndrome

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Posted on Fri, 25 Jul 2014
Question: Sir, My son, age-3 years is suffering from Child nephrotic syndrome for last one and half years. As per Doctor,s advice he is given wysolone 10 two times, azithral-xl liquid 200 once ( for 5 days). But swelling in his body is not reduced. How can I cure him completely?
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Answered by Dr. Omprakash Ashokrao Deshmukh (24 minutes later)
Brief Answer:
Treatment depends on the cause.

Detailed Answer:
Thanks for the query.
Children with neprotic syndrome are treated based on the cause, also it would take some time to decrease swelling.

A kidney biopsy to find the cause can be done.

But nephrotic syndrome can relapse anytime.

Monitor urine protien.

Furosemide (1 mg/kg/d) and spironolactone (2 mg/kg/d) will help to reduce swelling when fluid retention is severe.

Adequate energy (caloric) intake and adequate protein (1-2 g/kg/d) and no added salt will help to limit fluid overload.

If a child does not respond to steroids, another medicine called levamisole will be used alongside the steroids.

Other medicines that i will suggest if the symptoms do not respond to steroids and levamisole include cyclophosphamide, ciclosporin, tacrolimus and mycophenolate mofetil (after consulting the treating doctor).

Hope i help you.
Above answer was peer-reviewed by : Dr. Vinay Bhardwaj
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Answered by
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Dr. Omprakash Ashokrao Deshmukh

Pediatrician

Practicing since :2008

Answered : 633 Questions

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Suggest treatment for child nephrotic syndrome

Brief Answer: Treatment depends on the cause. Detailed Answer: Thanks for the query. Children with neprotic syndrome are treated based on the cause, also it would take some time to decrease swelling. A kidney biopsy to find the cause can be done. But nephrotic syndrome can relapse anytime. Monitor urine protien. Furosemide (1 mg/kg/d) and spironolactone (2 mg/kg/d) will help to reduce swelling when fluid retention is severe. Adequate energy (caloric) intake and adequate protein (1-2 g/kg/d) and no added salt will help to limit fluid overload. If a child does not respond to steroids, another medicine called levamisole will be used alongside the steroids. Other medicines that i will suggest if the symptoms do not respond to steroids and levamisole include cyclophosphamide, ciclosporin, tacrolimus and mycophenolate mofetil (after consulting the treating doctor). Hope i help you.