• question-icon

    Suggest treatment for breast cancer

default
Posted on Tue, 17 Feb 2015 in Cancer
Question: I am ER+PR+HER2 NEU. What does that mean and also how should it be treated. Currently I am being given Falsodex. I have had Arimidex. I am 2 years out from diagnosis, of metastic breast cancer, with peritoneal cancer that was told to be the breast cancer.
doctor
Answered by Dr. Grzegorz Stanko 38 minutes later
Brief Answer:
Your treatment seems to be correct.

Detailed Answer:
Hello!

Thank you for the query.

First of all few words about what receptor is. Please imagine a cancer cell as a rounded structure. It contains some proteins which are located on the surface of this structure. This proteins are used to allow communication between the inside of the cell and outside of the cell. This proteins are receptors. Now every receptor has specific regulator. To make it simple - receptor is a lock. To activate the lock, we need a specific key. This key is another protein which opens only one lock.

ER+ means that the cancer cells are Estrogen sensitive (contain estrogen receptors on theirs surface).
PR+ means that the cancer cells are Progesterone sensitive (contain progesterone receptors on theirs surface)
HER2/NEU is usually is described as positive or negative. If its negative, this is good. HER2/NEU receptor is a special one. If there is too much of it on the surface of the cell (positive) the cell can multiply very quickly. If its negative, it multiplies much longer. I assume your is negative.

Falsodex is a kind of "key" for estrogen receptor. But it does not unlock the receptor. It blocks it so the receptor do not send signals and in result, do not stimulate the cell to multiply. This is a way to stop cancer cells from growing. This treatment is chosen correctly. It should be used as long as the tests results will show cancer cells response to this treatment. In simple words, if there will be no cancer progression in CT or ultrasound.

If the tests will show no effectiveness of this medicine on some point, it will be switched to chemotherapy most likely. But this should be chosen by oncologist.

Hope this will help. Feel free to ask further questions.
Regards.
Above answer was peer-reviewed by : Dr. Raju A.T
doctor
Answered by
Dr.
Dr. Grzegorz Stanko

General Surgeon

Practicing since :2008

Answered : 5768 Questions

premium_optimized

The User accepted the expert's answer

Share on

Recent questions on  Peritoneal cancer

doctor1 MD

I am 61 yr old female, diagnosed with peritoneal cancer, had total hysterectomy one year ago, followed by six months of chemo, now on Avastin for...

doctor1 MD

I am currently taking Arimdex and Falsodex for treatment of metastic breast cancer and peritoneal cancer as result of the breast cancer. With...

doctor1 MD

my mother was diagnosed with peritoneal cancer stage 3. The doctors never made it clear if this was mesothelioma or not. Doing research peritoneal...

doctor1 MD

My sister has late stage primary peritoneal cancer. She had major surgery but they didn't get it all. After 4 rounds of chemo - her cancer is...

doctor1 MD

My mother has primary peritoneal cancer . She was diagnosed at Stage IIIC almost two weeks ago. Today, her legs are swollen from her thighs through...

doctor1 MD

Primary peritoneal versus primary ovarian carcinoma ,what is the best chemo to use,hoe effective?

Get personalised answers from verified doctor in minutes across 80+ specialties

127 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
Questions Answered By Dr. Grzegorz Stanko
  • Q - Nausea and hunger after eating, waking up at night hungry, urge to...

  • Q - Pain inside anus during bowel movement. Is Xyloproct or preparation H...

  • Q - Bad odor in belly button, red substance inside, oozing pus

  • Q - Pain in front of arm and at wrist under thumb, swelling and throbbing....

  • Q - Chest tightness when walking, upper back discomfort, heartburn, no...

  • Q - Lump in chest, painful, have pain in ribs and lower back

  • Q - Done hernia repair in belly button, have cramp on right side,...

  • Q - Frostbite wound on chest from blister freezer. Itching and peeling off....

  • Q - Vomiting, nausea, diarrhea, blood in urine. What do I do?

  • Q - Is triple action viriliy purchase thru new vitality safe?

backtotop2