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Suggest Treatment For Acute Myositis And Hyperthyroidism

Posted on Fri, 23 Jan 2015

Question: Hello, My Mother in law was diagnosed with Acute Myositis. She was hospitalised for 5 days where she was given IV drugs. Then on she is on Predmet 16 mg dosage since 2 months and her condition has improved about 60%. She also is a hyper thyroid. Thyroid levels also detected recently along with myositis.How long should she given this Predmet dosage yet ? As this drug has considerable side effects please help in getting us information as to how many more months she should be under this dosage.

Answered by Dr. Mukesh Chugh (34 minutes later)

Brief Answer:
Predmet is tapered depending upon response

Detailed Answer:
Hello
Thanks for posting
I have gone through your query and understand your concern.Never discontinue or reduce the dose without checking with your physician.

Tapering or slowly lowering the dose of corticosteroids is essential to allow body to begin cortisol production on its own.To have smooth transition from higher dose to lower dose,it is recommended to start immunosuppressant drugs like Methotrexate/azathioprine as secondline medicines or used in combination with prednisone. This allows patients to taper off prednisone more quickly and avoid some of the unwanted effects.

The blood test that can guide us is CRP(C reative protein) level.From daily dose of prednisolone it can be given on alternate days.You should discuss about this with your doctor.

Hope this helps and I shall be glad to answer any further query.
Take care

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Mukesh Chugh (2 hours later)

Thanks for the response. I would like 1 followup to this. Approximately how many days more it might take ? And please help me know how long she would still require to lift her legs and climb the steps. Presently she is'nt able to climb even 1 or 2 steps.

Answered by Dr. Mukesh Chugh (2 hours later)

Brief Answer:
It's difficult to predict exact time period

Detailed Answer:
Hello
You are welcome
I do understand your concern with the side effect but it's difficult to predict the exact time for recovery.Let me assure you 12mg is safe amount without much of serious side effects.
If even after 2 months of treatment on prednisone,
she is not able to walk around then her treatment needs to be reviewed.
My suggestions for her are-
1.Need to find out the cause for her myositis?
2.Get blood test done for creatinine kinase, complete blood count with CRP.
3.Add drug Methotrexate along with prednisone for early recovery.
You may discuss about these possibilities with your doctor/Rheumatologist.
Hope this answers your query.
Regards

Note: For further queries, consult a joint and bone specialist, an Orthopaedic surgeon. Book a Call now.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar