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Suggest the ideal dosage for Looz syrup taken for chronic constipation

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Posted on Mon, 25 Jul 2016
Question: MY SON, SHRI XXXXXXX DASH IS 13 YEARS AGE. HE IS SUFFERING FROM AUTISM AND CHRONIC CONSTIPATION. I GAVE HIM LOOZ SYRUP OF 10ML. FIRST TIME IT IS WORKING. NEXT TIME IT IS NOT WORKING. MY QUESTION IS (1) WHAT IS DAILY DOSE OF SYRUP OF 13 YEARS OLD BOY?
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Answered by Dr. Pradeep Kumar Jain (1 hour later)
Brief Answer:
Total daily dose is 1-3 ml/kg/day

Detailed Answer:
Hello

Thanks for asking on this platform

Looz contains lactulose,a laxative.
In chronic constipation the dose of lactulose is 1-3 ml/kg/day(maximum 60 ml/day). The average weight of 13 kg old child is around 35-40 kg;so the maximum dose which can be given is 60 ml/day. So the maximum dose that can be given is 15 ml/dose at an interval of 6 hours.

You have mentioned that you have given 10 ml of lactulose. It is not clear that how many dosage you have given. Once lactulose is given it may take 24-48 hours for the desired affect.

If already 48 hours have been passed and 2-3 dosage of lactulose each of 10 ml is given and there is no effect;you may increase the dose to 15 ml 6 hourly.

Side effect is mainly loose stools. If you notice frequent loose stools, hold the medication and give plenty of fluids to maintain the hydration.

I shall be glad to answer if you have any more doubts.
Regards



Above answer was peer-reviewed by : Dr. Arnab Banerjee
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Answered by
Dr.
Dr. Pradeep Kumar Jain

Pediatrician, Cardiology

Practicing since :2006

Answered : 2020 Questions

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Suggest the ideal dosage for Looz syrup taken for chronic constipation

Brief Answer: Total daily dose is 1-3 ml/kg/day Detailed Answer: Hello Thanks for asking on this platform Looz contains lactulose,a laxative. In chronic constipation the dose of lactulose is 1-3 ml/kg/day(maximum 60 ml/day). The average weight of 13 kg old child is around 35-40 kg;so the maximum dose which can be given is 60 ml/day. So the maximum dose that can be given is 15 ml/dose at an interval of 6 hours. You have mentioned that you have given 10 ml of lactulose. It is not clear that how many dosage you have given. Once lactulose is given it may take 24-48 hours for the desired affect. If already 48 hours have been passed and 2-3 dosage of lactulose each of 10 ml is given and there is no effect;you may increase the dose to 15 ml 6 hourly. Side effect is mainly loose stools. If you notice frequent loose stools, hold the medication and give plenty of fluids to maintain the hydration. I shall be glad to answer if you have any more doubts. Regards