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Suggest The Ideal Dosage For Aspirin Taken For DVT

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Posted on Tue, 26 Apr 2016
Question: I have been taking 325 mg of aspirin to prevent DVT due to a positive lupus like inhibitor blood test. I have had 2 more blood test to check the lupus like inhibitor and they have been negative. Do I need to be on aspirin and if so what dose, is it dangerous to stop taking aspirin cold turkey? Can I stop aspirin cold turkey can replace it with nattokinase supplement?
doctor
Answered by Dr. Ilir Sharka (2 hours later)
Brief Answer:
I would explain as follows:

Detailed Answer:
Hello!

Welcome and thank you for asking on HCM!

Regarding your concern, I would like to have some more information on your symptoms.

Do you have DVT symptoms (leg pain or swelling) or Lupus symptoms (joint paint, face redness, skin changes,etc.)?

What other tests have you performed for the diagnosis of DVT or Lupus?

As your Lupus antibodies have resulted negative twice there is real little chance for you to suffer from this disorder, and even more to suffer from a Lupus complication like DVT.

From the other hand, based on the XXXXXXX Heart Association guidelines aspirin is not effective in the prevention of DVT in high risk patients for this disorder. Anticoagulation therapy is needed for this purpose.

So I would recommend stopping aspirin if the diagnosis of Lupus has not been confirmed and you have no signs of possible DVT (with a normal Doppler ultrasound of the leg vessels and normal blood coagulation tests).

There is no reason to take aspirin.

Regarding nattokinase supplement, there is insufficient clinical based data to support its effects on the prevention of DVT in humans. So I would not recommend taking this supplement (even considering the fact that the diagnosis has not been confirmed).

Hope you will find this answer helpful!

Kind regards,

Dr. Iliri
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Ilir Sharka (3 hours later)
I have had numerous dopplers all negative, i am obese and need to lose weight but i am attaching all labs that have been done please note the dates on the reports. Thanks
doctor
Answered by Dr. Ilir Sharka (6 hours later)
Brief Answer:
Opinion as follows:

Detailed Answer:
Hi again,

I carefully reviewed your uploaded medical tests and would explain that they are quite normal, except for a slight increase of blood glucose level and glycosylated hemoglobin (HbA1c) level.

Your ANA, B2 Glycoproteins, Cardiolipin, LLI, INR are quite normal. No evidence of antiphospholipid syndrome or coagulation disorder is present.

So, relax!

There is no need for anticoagulation or anti-aggregation.

The only advice is to better control your body weight, as an elevated HbA1c level indicates increased risk of diabetes (HbA1c>5.6%) and lowering your body weight would avoid this metabolic syndrome and would lead to a better utilization of blood glucose levels.

I recommend following a healthy balanced diet, like Mediterranean diet and a physically active daily life-style profile.

Wishing you a pleasant weekend!

Greetings!

Dr. Iliri

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Ilir Sharka (41 hours later)
One more question, is 81 mg tylenol just as effective as 325 mg as far as the effect on platelets? Can i just take the 81 mg for about 2 weeks and the stop, i feel more comfortable doing that.


One more question, is 81 mg aspirin just as effective as 325 mg as far as the effect on platelets? Can i just take 81 mg for about 2 weeks and the stop aspirin, i feel more comfortable doing that.
doctor
Answered by Dr. Ilir Sharka (1 hour later)
Brief Answer:
Aspirin 81 mg is effective.

Detailed Answer:
Hello,

Yes! 81 mg Aspirin is as effective as 325 mg against platelets aggregation.

You can take 81 mg Aspirin daily instead of 325 mg.

Best regards,

Dr. Iliri
Note: For further queries related to coronary artery disease and prevention, click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Ilir Sharka

Cardiologist

Practicing since :2001

Answered : 9536 Questions

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Suggest The Ideal Dosage For Aspirin Taken For DVT

Brief Answer: I would explain as follows: Detailed Answer: Hello! Welcome and thank you for asking on HCM! Regarding your concern, I would like to have some more information on your symptoms. Do you have DVT symptoms (leg pain or swelling) or Lupus symptoms (joint paint, face redness, skin changes,etc.)? What other tests have you performed for the diagnosis of DVT or Lupus? As your Lupus antibodies have resulted negative twice there is real little chance for you to suffer from this disorder, and even more to suffer from a Lupus complication like DVT. From the other hand, based on the XXXXXXX Heart Association guidelines aspirin is not effective in the prevention of DVT in high risk patients for this disorder. Anticoagulation therapy is needed for this purpose. So I would recommend stopping aspirin if the diagnosis of Lupus has not been confirmed and you have no signs of possible DVT (with a normal Doppler ultrasound of the leg vessels and normal blood coagulation tests). There is no reason to take aspirin. Regarding nattokinase supplement, there is insufficient clinical based data to support its effects on the prevention of DVT in humans. So I would not recommend taking this supplement (even considering the fact that the diagnosis has not been confirmed). Hope you will find this answer helpful! Kind regards, Dr. Iliri