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Suggest Remedy For Tingling On Face With A History Of Perineural Invasion

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Posted on Mon, 14 Dec 2015
Question: Dear Sir/Madam
I had low grade mucoepidermoid carcinoma 4 years ago with perineural invasion. My upper 3 (three) branches of facial nerve was inside the tumor but I had no nerve palsy or weakness. Only thing I had formication( tingling and ant crawling on right face). My surgeon preserved the facial nerve by piecemeal excision of tumor and followed by radio therapy of 64 Gy. As there were microscopic particles inside the nerve and he told it will be cleared by radio therapy.
1) For last one month I have been experiencing tingling and formication over my right face and ear which I felt just before the surgery. Now I am experiencing that and I went to my surgeon and he told me I have no recurrence and prescribed neurobin forte. My concern is, can it possible of recurrence inside the FACIAL NERVE which is not visible to outside?
2) The risk due to piecemeal excision by nerve sparing technique has adverse effect on outcome. Can it be taken care by radio therapy?
3) What is the chance of cure in my case?
4) Does perineural invasion causes distant metastasis?
5) Is tingling on face and ear is normal after radio therapy as there is cn v nerve damage due to radiation?
Please read it carefully and reply. Thank You.

Thank You very much Sir.

1) My surgeon prescribed neurobin forte. Is it correct medication for fix the problem?
2)Is it possible of recurrence after 5 years of treatment? If yes, why it is called "cure" if there is no recurrence upto 5 years?
3) I do not have lympho-vascular invasion. Still is it possible for metastasis?
4) I have to follow 5 years or lifetime?

Thank You.
doctor
Answered by Dr. Dr. Ivan Romich (18 hours later)
Brief Answer:
hi again

Detailed Answer:
1. Well, neurobion is a B vitamin complex, I would add vitamin d more,it can be taken in form of drops or pills. These vitamins actually strengthen neurons and protect from further damage. It will not lead to nerve regeneration or something similar so you dont need to XXXXXXX if no noticeable effect will occur.
2. The possibility of recurrence after 5 years is very low, and it is considered that patient is cured if no signs are found. if tumor recur after that time then it is more likely to be new tumor. ALso, sometimes recurrence may occur within 5 years but symptoms or diagnostic signs are noticed 1,2 years later. All in all you can be very satisfied if no recurrence is found by now,this is very good prognostic sign.
3. Main risk for metastases is lymphovascular invasion and high tumor grade,you dont have none of these,so risk of metastais is possible but extremely low.
4. You should have standard follow ups for 5-6 years after surgery,but occasional clinical examination at your surgeon should last for lifetime. it doesnt mean that we expect recurrence or new tumor, but we want to examine possible complication of healing, irradiation, parotid gland function etc.


Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
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Follow up: Dr. Dr. Ivan Romich (5 hours later)
Thank You very much Sir.
My last question is
can you prescribe medication for nerve regeneration which will be helpful for me?
I have problem of tingling and formication on my right face and ear even after 4 years of radiation.
doctor
Answered by Dr. Dr. Ivan Romich (5 hours later)
Brief Answer:
no unfortunately

Detailed Answer:
Hi.
Well, unfortunately, such medications cant be prescribed online. Ask you GP which of these are available in your place. If you have any other question, feel free to ask. Regards
Above answer was peer-reviewed by : Dr. Arnab Banerjee
doctor
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Follow up: Dr. Dr. Ivan Romich (2 days later)
Tingling and formication continue even after taking neurobin forte. But my concern is
1) why it developed after a gap of 2 years? But sometimes it comes and goes for first 2 years from date of radiation.
2) I did not get radiation on ear. Why I feel formication all over ear?
3) Is it normal for anybody getting tingling after radiation throughout life?
Thanks.
doctor
Answered by Dr. Dr. Ivan Romich (4 hours later)
Brief Answer:
hi

Detailed Answer:
1. It is bit unusual that it happens with such delay but nerve inflammation process may have been triggered by variety of factors such as viral infection, stress, cold environment or it happens with no obvious cause as any other facial neuropathy can.
2. Formication may occur around radiation area, this is not strange. irradiation cant be perfectly directed and it may cause inflammation of tissue around it which then can affect distant parts of nerves
3. It is one of possible consequences

Thanks
Regards
Note: For further follow up on related General & Family Physician Click here.

Above answer was peer-reviewed by : Dr. Arnab Banerjee
doctor
Answered by
Dr.
Dr. Dr. Ivan Romich

General Surgeon

Practicing since :2008

Answered : 13886 Questions

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Suggest Remedy For Tingling On Face With A History Of Perineural Invasion

Brief Answer: hi again Detailed Answer: 1. Well, neurobion is a B vitamin complex, I would add vitamin d more,it can be taken in form of drops or pills. These vitamins actually strengthen neurons and protect from further damage. It will not lead to nerve regeneration or something similar so you dont need to XXXXXXX if no noticeable effect will occur. 2. The possibility of recurrence after 5 years is very low, and it is considered that patient is cured if no signs are found. if tumor recur after that time then it is more likely to be new tumor. ALso, sometimes recurrence may occur within 5 years but symptoms or diagnostic signs are noticed 1,2 years later. All in all you can be very satisfied if no recurrence is found by now,this is very good prognostic sign. 3. Main risk for metastases is lymphovascular invasion and high tumor grade,you dont have none of these,so risk of metastais is possible but extremely low. 4. You should have standard follow ups for 5-6 years after surgery,but occasional clinical examination at your surgeon should last for lifetime. it doesnt mean that we expect recurrence or new tumor, but we want to examine possible complication of healing, irradiation, parotid gland function etc.