Suggest remedy for steroid psychosis
Possible steroid psychosis.
I can certainly understand your concerns.
I have carefully gone through your daughter's medical issue in detail.
Based on her symptoms, she probably seem to have a condition known as steroid psychosis.
Steroid psychosis is a psychotic disorder caused by the use of corticosteroid medications. Affected people develop psychiatric symptoms such as depression and mania.
Researchers believe steroid psychosis occurs when high doses of corticosteroids cause an increase in dopamine levels in the brain. Increased dopamine levels lead to symptoms such as depression, mood swings and psychosis(hallucinations and illusions). Corticosteroids also lower the serotonin levels in the brain, worsening the patient's depressive symptoms.
Sleep pattern can be grossly deranged.
This condition can be treated by weaning off the steroid medications.
Additionally a short course of drugs like sedative anxiolytics like Clonazepam and Antipsychotics like Clozapine will help. I generally recommend my patients with such drugs. Please check with your physician if he shares my view and if can prescribe them to you.
The outcome is usually good.
Post your further queries if any.
Recommended tapering schedule provided.
I can surely understand your concern.
I apologize for the delayed response owing to my hectic work schedule.
The best tapering schedule is over 12 days instead of 14 days, as earlier stopping will help the adrenal gland to recover, adjust and function normally by making its own source of steroids.
The schedule I recommend is as follows.
Since your daughter is currently on 30 mg which is equivalent to 3 tabs of 10 mg each. Considering each tablet of 10mg-
Day 1 take 3 tablets
Day 2 take 3 tablets-30mg
Day 3 take 2 tablets-30mg
Day 4 take 2 tablets-20mg
Day 5 take 1.5 tablets-20mg
Day 6 take 1.5 tablets-20mg
Day 7 take 1 tablets-10mg
Day 8 take 1 tablets-10mg
Day 9 take 0.5 tablets-5mg
Day 10 take 0.5tablets-5mg
Day 11 take 0.25tablet-2.5mg
Day 12 take 0.25 tablet-2.5mg
For day last four days, it is advisable to go for liquid form of Prednisone, available as Prednisone Intensol(in case if you find difficulty in breaking the tablet into required dose). Each ml contains 5mg of prednisone. This will help for a fine tapering.
Day 1 can be taken as 18th Oct and Day 12 can be taken as Oct 29th.From 30th Oct you can stop the drug completely.
If symptoms are severe during the tapering , addition of clonazepam lowest doses will help to ease the process to successful outcome.
Please check with your physician if he can prescribe this tapering schedule to you.
Post your further queries if any,
You are always Welcome.
You are always Welcome.
You can ask me any further queries on my dashboard in future.
Hope everything will be fine.
My best wishes to you,your daughters and son in law.