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Suggest remedy for fever after reducing dosage of Arava

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Posted on Fri, 29 May 2015
Question: Reduced Arava to 10mg but she aged 56 years has 102'C fever what to do
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Answered by Dr. Swarnava Dattagupta (1 hour later)
Brief Answer:
give paracetamol; get complete hemogram and crp done

Detailed Answer:
Hello.
Welcome to HCM.
This is Dr. Swarnava Dattagupta answering your query.

I understand your concern.
Arava is leflunomide which is exclusively used in rheumatoid arthritis. Though you have not mentioned in history, i assume that she is suffering from RA.
Fever is a side effect of leflunomide but we need to rule out other infective causes. I would suggest you the following-

Do not reduce leflunomide dosage any further. 10mg is the least dose. What you can do is talk to your rheumatologist. He/she might change it to other drug if needed.
You can give her paracetamol 650 tablets thrice daily for 2 days and then if needed.
You can get a complete hemogram and a c-reactive protein or CRP done. It would detect any possible infective foci.
You can give her cold sponging.
Give her soft, healthy diet.

Get back to me with the reports and give a followup about her condition.
Hope this was useful.
Regards.
Above answer was peer-reviewed by : Dr. Prasad
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Answered by
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Dr. Swarnava Dattagupta

General & Family Physician

Practicing since :2013

Answered : 906 Questions

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Suggest remedy for fever after reducing dosage of Arava

Brief Answer: give paracetamol; get complete hemogram and crp done Detailed Answer: Hello. Welcome to HCM. This is Dr. Swarnava Dattagupta answering your query. I understand your concern. Arava is leflunomide which is exclusively used in rheumatoid arthritis. Though you have not mentioned in history, i assume that she is suffering from RA. Fever is a side effect of leflunomide but we need to rule out other infective causes. I would suggest you the following- Do not reduce leflunomide dosage any further. 10mg is the least dose. What you can do is talk to your rheumatologist. He/she might change it to other drug if needed. You can give her paracetamol 650 tablets thrice daily for 2 days and then if needed. You can get a complete hemogram and a c-reactive protein or CRP done. It would detect any possible infective foci. You can give her cold sponging. Give her soft, healthy diet. Get back to me with the reports and give a followup about her condition. Hope this was useful. Regards.