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Stopped Taking Efient. Developed Severe Itching All Over Body. How Long Will It Take To Recover?

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Posted on Mon, 8 Jul 2013
Question: I was taking efient (effient in us) stopped taking it 6weeks ago. While on this medication I developed severe itching over my body. I still have the itching, Now, assuming that the efient caused the itching: How long will it take for the itching to go?
doctor
Answered by Dr. Ram Choudhary (1 hour later)
Hi Me.
Welcome to Healthcare Magic.
6 weeks is a pretty long time for a drug reaction effect to last.
Do you have any skin lesions also apart from itching.
Please let me know the content of Effient in your country.
What are your other current medicines
Please let me know in the follow up.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Ram Choudhary (5 hours later)
I have no skin lesions; just the itching.

Efient (UK spelling)
Active is 10mg prasugrel.
Other ingredients are microcrysaline cellulose, mannitol (E421), croscarmellose sodium hypromellose (E464), magnesium stearate, titanium dioxide (E171), triacetin (E1518), iron oxide red (E172), iron oxide yellow (E172).

Other medication: an anti-histamine pill.
doctor
Answered by Dr. Ram Choudhary (36 hours later)
Hi Me,
Welcome back.
The Prasugrel is highly unlikely to be a cause for such a prolonged itching.
May some other medicine called ACE inhibitors have started this.
Please check your liver function test also as a cause for this as a result of some other intercurrent illness.
Sometimes there can be simple urticaria which causes such itching but in this the itching comes in episodes and has temporary raised skin lesion which vanish in 1-2 hours.
Taking an antihistaminic for 1-2months is a good idea.
I hope the advise will be helpful for you.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Ram Choudhary (3 hours later)
Following up your suggestion that some other medicine called ACE inhibitors might have started the itching then could this itching still persist after longer than 6weeks now?
doctor
Answered by Dr. Ram Choudhary (10 hours later)
Hi Me,
Welcome back.
First make sure if you had any medicine of this group, they have similar names like ramipril, lisinopril,fosinopril etc.
By 6weeks the effect start fading out in these cases but antihistaminics help uniformly and future exposure to the causative drug should be avoided.
I hope the advise would be helpful.
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Ram Choudhary

Internal Medicine Specialist

Practicing since :2001

Answered : 2270 Questions

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Stopped Taking Efient. Developed Severe Itching All Over Body. How Long Will It Take To Recover?

Hi Me.
Welcome to Healthcare Magic.
6 weeks is a pretty long time for a drug reaction effect to last.
Do you have any skin lesions also apart from itching.
Please let me know the content of Effient in your country.
What are your other current medicines
Please let me know in the follow up.