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Dr. Andrew Rynne

Family Physician

Exp 18 years

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Pregnant. Will it be safe to take duphaston 10mg and loprin 75mg?

May 2013
User rating for this question
Very Good
Answered by
Practicing since : 2006
Answered : 4943 Questions
Hi Doctor,
My wife is 30 years old, had her first miscarriage (1st conception) 3 months back (no DNC). now she is 4 Weeks & 4 Days pregnant, and her doctor has prescribed, Duphaston 10mg 2/day+Loprin 75mg 1/day.
My question :
1. Are these drugs necessary, as she conceived naturally both the times?
2. If taken what are the side effects of these drugs?
Tue, 11 Dec 2012 in Pregnancy
Answered by Dr. Sree Gouri SR 1 hour later
Thanks for the query.

Though your wife conceived naturally, the doctor might have kept her on these drugs as a preventive measure because she had previous abortion.
Duphaston which is a progesterone, will help in maintenance of pregnancy and in preventing premature uterine contractions.
It can cause side effects like nausea, vomitings, bloating sensation etc.
Aspirin also helps in preventing abortion due to conditions like hypertensive disorders, fetal growth retardation etc.
It can also cause general side effects like gastritis, bowel disturbances, drop in prostaglandins production etc.
But usually doctors will prescribe these drugs as benefits over weigh the risks here.

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