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Pregnant. Took flurbiprofen twice today contained in throat lozenge. Worry?

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Posted on Fri, 29 Jun 2012
Question: Took 8.75 mgs flurbiprofen twice today contained in throat lozenge. Im 27 weeks pregnant and worried.
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Answered by Dr. Hema Yadav (4 hours later)
Hello ,
Thanks for posting your query.
Flurbiprofen is an Nonsteroidal Antiinflammatory drug (Nsaid)& like other Nsaids it is contraindicated in third trimester of pregnancy and early pregnancy.
There is a risk of premature closure of ductus arteriosus in the fetus and oligohydramnios if it is taken after 30 weeks of pregnancy.
The avilable data does not suggest any such risk before 30 weeks of pregnancy.
Also the risk is dose related and chances increase with the advancement of pregnancy beyond 30 weeks.
In case of inadvertent ingestion of flurbiprofen by pregnant female, it is advisable to report the issue to the gynaecologist and if needed get an ultrasound done to monitor for closure of ductus arteriosus or oligohydramnios.
In your case both the dose taken (8.75 mg twice) and the duration of pregnancy (27 weeks) make it less likely for the chance of such complication to your fetus.
So please do not worry as it is not likely that you will suffer any of the above mentioned comolication.
However it is advisable to report this to your doctor and if in the next couple of weeks if the doctor suspects any risk he might get an ultrasound done .
As of now it's not worrisome, but in future do not take any medication without your doctors advice
Hope I have answered your query.
Regards
Above answer was peer-reviewed by : Dr. Raju A.T
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Answered by
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Dr. Hema Yadav

Pediatrician, Infectious Diseases

Practicing since :2005

Answered : 1528 Questions

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Pregnant. Took flurbiprofen twice today contained in throat lozenge. Worry?

Hello ,
Thanks for posting your query.
Flurbiprofen is an Nonsteroidal Antiinflammatory drug (Nsaid)& like other Nsaids it is contraindicated in third trimester of pregnancy and early pregnancy.
There is a risk of premature closure of ductus arteriosus in the fetus and oligohydramnios if it is taken after 30 weeks of pregnancy.
The avilable data does not suggest any such risk before 30 weeks of pregnancy.
Also the risk is dose related and chances increase with the advancement of pregnancy beyond 30 weeks.
In case of inadvertent ingestion of flurbiprofen by pregnant female, it is advisable to report the issue to the gynaecologist and if needed get an ultrasound done to monitor for closure of ductus arteriosus or oligohydramnios.
In your case both the dose taken (8.75 mg twice) and the duration of pregnancy (27 weeks) make it less likely for the chance of such complication to your fetus.
So please do not worry as it is not likely that you will suffer any of the above mentioned comolication.
However it is advisable to report this to your doctor and if in the next couple of weeks if the doctor suspects any risk he might get an ultrasound done .
As of now it's not worrisome, but in future do not take any medication without your doctors advice
Hope I have answered your query.
Regards