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On Synthroid 200mcg. Having Bone Pain, Petechiae On Stomach And Feeling Fatigued. Any Ideas?

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Posted on Tue, 4 Dec 2012
Question: Hi, I have been suffering with poor health for a few years, some days better than others. I started with the diagnosis of a pituitary adenoma. I have low FH, LH, and a high TSH all of which I a taking supplements for. I am taking 200 mcgs of synthroid and each time I have blood work, my dosage is increased. My endocrinologist does not want to take out the adenoma at this time. I have a lot of bone pain, particularily in my hips, lower, and middle back. I have extreme fatigue now, which is opposite prior to getting sick. I noticed petechiae all over my stomach, arms, and now on my breasts. Worst of all I have gained 70lbs. in 2 years. I am a health nut, I don't drink, or smoke. Before all of this I weighed 120 lbs., perfect for my 5'3" frame. What a mess!
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Answered by Dr. Ram Choudhary (3 hours later)
Hi XXXXXXX,
Thanks for writing in to Healthcare Magic!
The adenomas of pituitary are known to cause a hormonal imbalance among other endocrine systems, your thyroid funtion has been hit badly, and the replacement is necessary by Synthroid as the blood work suggests.
The weight gain suggests the hormonal turmoil.
The rash and bone pain is unexpected in pituitary adenomas.
You should get examined by a physician of the locality and get work up to rule out Multiple myeloma or secondaries, get CBC, RFT, LFT, INR, skull and pelvic bone Xrays, Serum electrophoresis for M-spike.
A bone scan can detect if you have any secondary deposits of the tumor.
If you do not get any other major trouble in the work-up then it is time to act on adenoma itself.
Pituitary adenoma can be surgically resected or can shrink in size by radiotherapy.
I hope the advise would be helpful for you.
Note: For further follow up on related General & Family Physician Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Ram Choudhary

Internal Medicine Specialist

Practicing since :2001

Answered : 2270 Questions

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On Synthroid 200mcg. Having Bone Pain, Petechiae On Stomach And Feeling Fatigued. Any Ideas?

Hi XXXXXXX,
Thanks for writing in to Healthcare Magic!
The adenomas of pituitary are known to cause a hormonal imbalance among other endocrine systems, your thyroid funtion has been hit badly, and the replacement is necessary by Synthroid as the blood work suggests.
The weight gain suggests the hormonal turmoil.
The rash and bone pain is unexpected in pituitary adenomas.
You should get examined by a physician of the locality and get work up to rule out Multiple myeloma or secondaries, get CBC, RFT, LFT, INR, skull and pelvic bone Xrays, Serum electrophoresis for M-spike.
A bone scan can detect if you have any secondary deposits of the tumor.
If you do not get any other major trouble in the work-up then it is time to act on adenoma itself.
Pituitary adenoma can be surgically resected or can shrink in size by radiotherapy.
I hope the advise would be helpful for you.