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My daughter, 25-year-old married, had pregnancy miscarriage 16 months ago.

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Posted on Thu, 3 Jan 2019
Question: My daughter, 25-year-old married, had pregnancy miscarriage 16 months ago. Now, she is pregnant since one month about and she has been informed by the doctor, throughout medical checkup, that she is infected with Herpes virus which may cause miscarriage again.
Doctor prescribes her to use Aciclovir 200mg five times a day, but when begins using the medicine she experience abdominal pain.
My concern is 1. Does Herpes virus cause miscarriage? 2. is there any alternative medicine? 3. What is the best cure for such case and prevent miscarriage?
doctor
Answered by Dr. Vaishalee Punj (1 hour later)
Brief Answer:
No medicine to prevent miscarriage

Detailed Answer:
Hello and welcome to Ask A Doctor service.

I have reviewed your query and here is my advice.

Firstly I could not find herpes reports in attached reports. the report is about CMV.
CMV or Herpes virus doesnot cause miscarriage. Presence of active herpes or CMV infection may cause infection of baby during delivery if there is genital infection. In rare cases active infection maybe a cause of miscarriage.

Acyclovir is category B drug for use in pregnancy. A few doses should not harm but continuous use should be avoided in pregnancy.

As such no medicine to prevent miscarriage. She can simply take her precautions of taking rest and avoid lifting heavy weights.

Hope this helps. Let me know if I can assist you further.
Dr Vaishalee
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Follow up: Dr. Vaishalee Punj (1 hour later)
Is there any alternative medicine instead of Acyclovir, as it causes abdominal pain?
What is the use of Acyclovir? Finally, how harm is CMV?
doctor
Answered by Dr. Vaishalee Punj (14 hours later)
Brief Answer:
Hyper-immune globulin

Detailed Answer:
Hi again

Thanks for reverting back with doubts.

CMV IgG is practically detectable in most people on serologic screening. Abortion with it is rare, and fetal infection or abnormality is also uncommon. An ultrasound during pregnancy is needed to find if there is fetal abnormality.

Since your daughters IgM is negative, it means that she doesnot have active infection. So her baby getting affected is rare. We can also send her blood sample to find if there is any virus present. Otherwise unnecessay medicines are not needed.

Acyclovir is an anti-viral medicine. It kills some of the viruses but not all.
Hyperimmune globulin is recommended in pregnancy as prophylaxis.
Valacyclovir and famcyclovir are other alternatives.

Hope this clears your doubt. Feel free to write back.
Dr Vaishalee
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Dr. Vaishalee Punj

General & Family Physician

Practicing since :2003

Answered : 2415 Questions

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My daughter, 25-year-old married, had pregnancy miscarriage 16 months ago.

Brief Answer: No medicine to prevent miscarriage Detailed Answer: Hello and welcome to Ask A Doctor service. I have reviewed your query and here is my advice. Firstly I could not find herpes reports in attached reports. the report is about CMV. CMV or Herpes virus doesnot cause miscarriage. Presence of active herpes or CMV infection may cause infection of baby during delivery if there is genital infection. In rare cases active infection maybe a cause of miscarriage. Acyclovir is category B drug for use in pregnancy. A few doses should not harm but continuous use should be avoided in pregnancy. As such no medicine to prevent miscarriage. She can simply take her precautions of taking rest and avoid lifting heavy weights. Hope this helps. Let me know if I can assist you further. Dr Vaishalee