My HBa2 Is 5.8 ( Beta-thalassemia Trait ) And My
Molecular testing to detect Hb mutation for your family is suggested
Thanks for posting your query on Ask A Doctor forum.
The haemoglobin electrophoresis reports give a clear picture that you and your husband have elevated HbA2 which is suggestive of thalassemia trait.
These results should be followed by molecular tests for detecting mutations in haemoglobin chain.
You have had a one year old child with 20% fetal haemoglobin which is high as compared to normal range for age.
In addition, there is elevated level of HbA2 also.
Your child also needs to undergo molecular test.
I would suggest you to get the molecular test done before planning second pregnancy.
In addition, subsequent pregnancies should be tested for any mutation during pre-natal period.
Since, both you and your husband have thalassemia trait, precautions in the form of counselling and pre-natal testing should be done to avoid any pregnancy with thalassemia major or intermedia.
Thanks and take care
Dr Shailja Puri