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Is there interaction between Mebendazole and Praziquantel?

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Posted on Thu, 28 Jul 2016
Question: How long after taking Mebendazole for Ascaris (for three days) to take Praziquantel for intestinal flukes?
doctor
Answered by Dr. Saumya Mittal (34 minutes later)
Brief Answer:
1 day

Detailed Answer:
Hi,
I am Dr Mittal.
I have read your message.
I think I can help you.
Just 1 day of therapy is usually enough.
It may be repeated in 4 to 6 weeks if needed.
Best of luck. Dr Mittal
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Saumya Mittal (11 minutes later)
Thank you! I am still waiting for the Mebendazole to kick in-- just finished my final dose tonight. Is it normal to take a few more days to get the Ascaris out? How do you know if you have a systemic versus intestinal infection?

Also, having tight, stabbing sensations throughout the ribs, where I typically have varying degrees of constant pain. Is this an indication that the medicine is working?
doctor
Answered by Dr. Saumya Mittal (12 hours later)
Brief Answer:
Specific information

Detailed Answer:
Hi,

Mebendazole will work.
You have to take Praziquental thereafter.
Ascaris flushing will take time.

There's no specific way to find out if it's systemic or intestiall. However, the medicines will work just the same.

The tight sensation is a part of infection. It will clear slowly as the infection clears.
I hope have responded as per your questions.

Best of luck.
Dr Mittal
Above answer was peer-reviewed by : Dr. Arnab Banerjee
doctor
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Follow up: Dr. Saumya Mittal (14 hours later)
Thanks very much. How long does the ascaris flushing take typically?
doctor
Answered by Dr. Saumya Mittal (8 minutes later)
Brief Answer:
7 to 15 days

Detailed Answer:
Hi,
The period is variable.
it depends on the parasitic load.
Usually 7 to 15 days.
Best of luck. Dr Mittal
Above answer was peer-reviewed by : Dr. Yogesh D
doctor
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Follow up: Dr. Saumya Mittal (15 hours later)
Do you recommend a second round after two weeks to get the hatched eggs missed the first round?
doctor
Answered by Dr. Saumya Mittal (2 hours later)
Brief Answer:
No

Detailed Answer:
Hi
I won't recommend a second course just yet.
However , I would suggest that you test with a stool routine test. Of course, if the signs of infection persist on the stool test then a second course is warranted.
Hope you are on antacids with antibiotics.
Best of luck. Dr Mittal
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Saumya Mittal (1 hour later)
OK thank you! I'm not on any antacids or antibiotics. What medicines/ dosages do you recommend? Is it possible to use Oregano Oil for the infection?
doctor
Answered by Dr. Saumya Mittal (4 hours later)
Brief Answer:
Pantocid

Detailed Answer:
You can try Pantoprazole 40 mg twice a day on empty stomach.
I am unaware about the actions of the oil

Brief Answer:
most times the 1st repeat course is same

Detailed Answer:
most times the 1st repeat course is same
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Saumya Mittal (8 hours later)
Okay thank you. Which antibiotics and dosage?

Sorry! I'm confused about if I need to take an antibiotic now (after having taken vermox.)
doctor
Answered by Dr. Saumya Mittal (1 hour later)
Brief Answer:
Suggestions

Detailed Answer:
You need to complete the current dose of antibiotics.
Then wait 15 to 20 days.
Test stool routine.
If infection persists, a cycle may be repeated
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Saumya Mittal (2 days later)
Is it possible to use albendazole for the second round if needed? Or should I stick with mebendazole? I have had this for 20 years and want to be completely sure I get it! Symptoms are throughout the rib cage.
doctor
Answered by Dr. Saumya Mittal (1 hour later)
Brief Answer:
Can be taken

Detailed Answer:
Hi,
Yes Albendazole can be used.
Best of luck.

Above answer was peer-reviewed by : Dr. Prasad
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Follow up: Dr. Saumya Mittal (7 hours later)
Is albendazole more effective?
doctor
Answered by Dr. Saumya Mittal (46 minutes later)
Brief Answer:
No

Detailed Answer:
No such thing.
However, the dose of Albendazole is less .
Still effects of Mebendazole and Albendazole are comparable at the end of the course.

Best of luck.
Above answer was peer-reviewed by : Dr. Arnab Banerjee
doctor
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Follow up: Dr. Saumya Mittal (23 hours later)
Will the second round, if needed, definitely resolve the infection? How long does it usually take for people to resolve a long term infection?
doctor
Answered by Dr. Saumya Mittal (2 hours later)
Brief Answer:
1 is enough

Detailed Answer:
Most of the times 1 round is enough.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Saumya Mittal (11 days later)
It's been 19 days since taking Vermox. In the past 10 days I have had an increasing pain in the upper left abdomen under the ribs (stomach area). It is now an intense stabbing sensation. Is it possible that a worm is stuck? I am worried that I may not have achieved full absorption of the Vermox because I take Linzess for constipation. Is that possible?
doctor
Answered by Dr. Saumya Mittal (3 hours later)
Brief Answer:
Meet a gastroenterology specialist

Detailed Answer:
Hi,
I think you should meet a gastroenterology specialist.
There is a possibility that the infection may have affected the gall bladder.
I can't examine you.
Best to meet a gastroenterology specialist for a endoscopy.
Meanwhile, test an ultrasound of the abdomen.
Best of luck.
Dr Mittal
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Saumya Mittal (2 hours later)
Should I not take the second round of Vermox due to symptoms?
doctor
Answered by Dr. Saumya Mittal (4 hours later)
Brief Answer:
Better to meet a gastroenterology specialist first

Detailed Answer:
Hi
I think I would suggest meeting with the gastroenterology specialist first
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Saumya Mittal (7 days later)
Hi, how long does it take for the Praziquantel to work after taking it for flukes (fasciolopsis buski)? I took the 25 mg per kg 3x for one day.
doctor
Answered by Dr. Saumya Mittal (2 hours later)
Brief Answer:
1 week

Detailed Answer:
Hi
What did your local practitioner, who prescribed it, tell you?

Above answer was peer-reviewed by : Dr. Yogesh D
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Answered by
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Dr. Saumya Mittal

Diabetologist

Practicing since :2004

Answered : 2895 Questions

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Is there interaction between Mebendazole and Praziquantel?

Brief Answer: 1 day Detailed Answer: Hi, I am Dr Mittal. I have read your message. I think I can help you. Just 1 day of therapy is usually enough. It may be repeated in 4 to 6 weeks if needed. Best of luck. Dr Mittal