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Is there any treatment for Inclusion body myositis?

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Posted on Wed, 22 Jan 2014
Question: Is there any progress on curing or treating Inclusion body myositis?
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Answered by Dr. Michelle Gibson James (36 minutes later)
Brief Answer: no effective medication as yet Detailed Answer: Hi, thanks for using healthcare magic This condition is one of the most common age related muscle disease seen in older persons. It is associated with progressive inflammation of the muscles, with infiltration of the muscles. In addition to the muscle weakness in different aspects of the body, some persons may also have difficulty swallowing. In terms of treatment options, at present, unfortunately there is no definitive effective treatment. (1) high dose steroids actually worsen strength while they decrease inflammation (2)They are currently some studies being done to evaluate new therapies such as (a)arimoclomol- an initial study showed that this medication has promise in helping persons with this condition but further studies are needed to confirm this. (b)studies are assessing the usefulness of a medication called etanercept (3)alemtuzumab- initial studies showed that this slowed down the progression of the disease and also increased strength in some persons but again , further studies are to be done (4) gene therapy is also being evaluated At present , these medications are still being evaluated and it would be some time before they are available for general use. I hope this helps, feel free to ask any other questions
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Michelle Gibson James

General & Family Physician

Practicing since :2001

Answered : 16810 Questions

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Is there any treatment for Inclusion body myositis?

Brief Answer: no effective medication as yet Detailed Answer: Hi, thanks for using healthcare magic This condition is one of the most common age related muscle disease seen in older persons. It is associated with progressive inflammation of the muscles, with infiltration of the muscles. In addition to the muscle weakness in different aspects of the body, some persons may also have difficulty swallowing. In terms of treatment options, at present, unfortunately there is no definitive effective treatment. (1) high dose steroids actually worsen strength while they decrease inflammation (2)They are currently some studies being done to evaluate new therapies such as (a)arimoclomol- an initial study showed that this medication has promise in helping persons with this condition but further studies are needed to confirm this. (b)studies are assessing the usefulness of a medication called etanercept (3)alemtuzumab- initial studies showed that this slowed down the progression of the disease and also increased strength in some persons but again , further studies are to be done (4) gene therapy is also being evaluated At present , these medications are still being evaluated and it would be some time before they are available for general use. I hope this helps, feel free to ask any other questions