Is there any relationship between CFS and EBV infection?
I was tested a month ago for several viruses by the Urgent Care doctor I saw after having a bad interaction (Requip, Norco, and Tenazadine). And, while I am not active for these (EBV, CMV, HHV-6), I had an extremely high IgG for EBV (270 versus the positive range of >21). I am aware that 90 percent of the population has had these viruses at one time or another; however, because of the amount of antibodies in my bloodstream, could I still be having symptoms of EBV? I am trying to be more active, but I'm not doing very well, feeling like I have a case of the flu magnified, each time I attempt even the mildest of exercise (like trick-or-treating with my grandkids Saturday night). I awoke the next morning with a migraine headache. I slept all day Monday... just now regaining my strength today. Could this be CFS?
?CFS ?Chronic active EBV infection
Thank you for your query. I can understand your concerns.
Patients with chronic fatigue syndrome (CFS) may have titers of antibody
to EBV that are elevated but are not significantly different from those
in healthy EBV-seropositive adults. While some patients have malaise
and fatigue that persist for weeks or months after IM, persistent EBV
infection is not a cause of chronic fatigue syndrome.
So it is unlikely you are having CFS.
Chronic active EBV infection is very rare and is distinct from chronic fatigue syndrome.The affected patients have an illness lasting >6 months, with
elevated levels of EBV DNA in the blood, high titers of antibody to
EBV, and evidence of organ involvement, including hepatosplenomegaly,
lymphadenopathy, and pneumonitis, uveitis, or neurologic disease.
Since you don't have any organ involvement ,Chronic active EBV infection is also not a possibility.
However you can go for EBV DNA -PCR( polymerase chain reaction )as IgG antibody for EBV is high .
IgG antibody is often used to assess past exposure to EBV because it persists for life.
Dr. T.K. Biswas M.D. XXXXXXX
I apologize for not providing you a more detailed history in order to produce a more accurate diagnosis. I was trying to keep things simple. I guess there's nothing simple about it. Is it possible that all of this could be related?
?Chronic active EBV infection
In view of organ involvement liver and renal failure and stroke (neurological involvement) and high IgG titre for EBV (270 versus the positive range of >21),
Chronic active EBV infection is likely and it often mimics chronic fatigue syndrome.The diagnosis will be substantiated by elevated levels of EBV DNA in the blood ( as suggested already to undergo the PCR test).
Except for cardiac arrhythmia,all other features could be explained by Chronic active EBV infection.
Dr. T.K. Biswas M.D. XXXXXXX
The User accepted the expert's answer
Get personalised answers from verified doctor in minutes across 80+ specialties
- Is ebv infection contagious and how is it acquired
- Ebv infection causes
- Drugs/medication for ebv infection
- Symptoms of ebv infection
- Why hepatomegaly in ebv infection
- Diagnosis of ebv infection
- What is the permanent cure for ebv infection
- Could ebv infection lead to thyroid problems
- Treatment and cure for ebv infection
- Reactivated ebv infection and bronchitis