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Is There A Time Period Within Which Wakalert Becomes Effective In Plasma Levels?

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Posted on Mon, 4 Apr 2022
Question: Dear Doctor
Do we have a time period where the wakalert will become effective in plasma levels ?
Modalert works the same day.

Thank you
doctor
Answered by Dr. Dr. Ashok Kumar Choudhary (50 minutes later)
Brief Answer:
Consultation

Detailed Answer:

Hello,

Wakalert (Armodafinil) either shows effect within three days or does not show any effect. As per the available literature the effect is evident in 48-72 hours and if there is no effect probably it will not show any effect to the particular individual.

The same is true for modafinil but it does not mean that both molecules will be effective in the similar manner. However it is always better to try higher dose of medication if lower dose does not show effect or the effect is inadequate. As per my own experience I have seen at least thirty individuals who have not responded to armodafinil despite showing good effect with modafinil.

In other words it can be stated that if the lower dose doses not show effect higher dose can be used. In case that also does not show any effect abandoning the medication will be right strategy.

I hope this helps you. Feel free to write back to me if you have more questions.
Thanks and regards.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr. Ashok Kumar Choudhary (2 hours later)
Thanks doctor.
Was there a correlation between modafinil and blood flow to lower extremities ?
I know there is no causal logic. I feel calf muscle uneasiness only as a side effect.
doctor
Answered by Dr. Dr. Ashok Kumar Choudhary (15 hours later)
Brief Answer:
No such correlation known

Detailed Answer:

Hello,

Regarding the correlation of blood flow and modafinil I do not think there is any study of such nature. It is possible that there might be some correlation but this is not proved scientifically and cannot be more than a simple guesswork.

However it is true that uneasiness is known side effect of modafinil which can be experienced in any part of body including calf muscles.

I hope this helps you further.
Thanks and regards.
Note: In case of any other concern or query related to prevention, evaluation, diagnosis, treatment, or the recovery of persons with the any type of addiction or substance use, follow up with our Addiction Medicine Specialist. Click here to book a consultation now.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Dr. Ashok Kumar Choudhary

Psychiatrist

Practicing since :2000

Answered : 3354 Questions

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Is There A Time Period Within Which Wakalert Becomes Effective In Plasma Levels?

Brief Answer: Consultation Detailed Answer: Hello, Wakalert (Armodafinil) either shows effect within three days or does not show any effect. As per the available literature the effect is evident in 48-72 hours and if there is no effect probably it will not show any effect to the particular individual. The same is true for modafinil but it does not mean that both molecules will be effective in the similar manner. However it is always better to try higher dose of medication if lower dose does not show effect or the effect is inadequate. As per my own experience I have seen at least thirty individuals who have not responded to armodafinil despite showing good effect with modafinil. In other words it can be stated that if the lower dose doses not show effect higher dose can be used. In case that also does not show any effect abandoning the medication will be right strategy. I hope this helps you. Feel free to write back to me if you have more questions. Thanks and regards.