Is salvage radiation therapy recommended after radical prostatectomy for prostate cancer?

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Posted on Wed, 10 Jun 2015 in Cancer
Question: Radical prostate surgery Aug 2003 (PSA = 7) pathologist report: XXXXXXX 3+4, one positive margin, otherwise tumor confined to prostate. Initial PSA 1 month after surgery = 0.1 ng/mL; XXXXXXX slowly over 10 years to 0.3 (or 0.4). Over last 1 1/2 years has risen to 0.6 [the following tests were at 6 month intervals] starting (9/2013)... 0.3 ---> 0.4 -----> 0.5 ----> 0.6 (4/2015). Doubling time (DT) over first 10 years following surgery ~ 5 year; (DT) over last 1.5 year = 18 months. Do you recommend salvage radiation therapy at this point ?
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Answered by Dr. Indranil Ghosh 3 hours later
Brief Answer:
yes

Detailed Answer:
Hi
Thanks for your query.

The standard recommendation for salvage radiation after radical prostatectomy is a PSA of 0.2 ng/ml. In your case it has touched this level sometime back and is showing increasing trend. Hence I definitely recommend salvage RT.


Hope this answers your query. I will be available for follow up.
Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Indranil Ghosh

Oncologist

Practicing since :2004

Answered : 1513 Questions

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