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Is Recurrence Of Depression Possible While Weaning Off Viibryd?

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Posted on Wed, 24 Jun 2015
Question: How do I carefully wean myself off of 30 mg. Viibryd to start taking 20 mg. of Lexapro. I get worried that while I am weaning myself off I will fall into depression.
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Answered by Dr. Muhammad Hanif (4 hours later)
Brief Answer:
Follow the instructions and you will not fall into depression.

Detailed Answer:
Dear XXXX!

I welcome you at my Virtual Clinic. I have carefully gone through your question and understand your concerns.

The Viibryd is highly bound to plasma proteins and so if you take it concomitantly along with another drug of the same class i.e Lexapro (SSRI's), it will increase the free plasma concentration of Lexapro and that's dangerous.
Taper from 30mg to 15mg per day for 4 days, and then 10mg per day for 7 days. And then you should start with 10mg per oral Laxapro once daily. Your physician may increase Lexapro from 10mg to 20mg per day after 7days. But we have to maintain the minimum effective dosage if needed for longer time periods.

Hope I helped answer you sufficiently. Please don't forget to give a good feedback review and high star rating to this case so that I may be in a better position to help you in future. You may "Ask me a direct question" from my profile in future if needed any other help.

Regards!
Dr. Hanif XXXXXXX USA
Note: For further guidance on mental health, Click here.

Above answer was peer-reviewed by : Dr. Vinay Bhardwaj
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Answered by
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Dr. Muhammad Hanif

General & Family Physician

Practicing since :2009

Answered : 2369 Questions

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Is Recurrence Of Depression Possible While Weaning Off Viibryd?

Brief Answer: Follow the instructions and you will not fall into depression. Detailed Answer: Dear XXXX! I welcome you at my Virtual Clinic. I have carefully gone through your question and understand your concerns. The Viibryd is highly bound to plasma proteins and so if you take it concomitantly along with another drug of the same class i.e Lexapro (SSRI's), it will increase the free plasma concentration of Lexapro and that's dangerous. Taper from 30mg to 15mg per day for 4 days, and then 10mg per day for 7 days. And then you should start with 10mg per oral Laxapro once daily. Your physician may increase Lexapro from 10mg to 20mg per day after 7days. But we have to maintain the minimum effective dosage if needed for longer time periods. Hope I helped answer you sufficiently. Please don't forget to give a good feedback review and high star rating to this case so that I may be in a better position to help you in future. You may "Ask me a direct question" from my profile in future if needed any other help. Regards! Dr. Hanif XXXXXXX USA