Dear patient

Thanks for your health concerns. Premarin are conjugated equine estrogens, and despite the fact that we dont have comparative randomized trials between those 2 options, conjugated equine estrogens have a proven record of efficacy and have been used since the 1970's. Thus I think your provider has suggested a very reasonable alternative. The side effect profile is similar, but you should consult your provider if you notice any adverse or unusual reaction

yours truly

Dr Brenes Salazar
Mayo Clinic

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usually it takes at least half a menstrual cycle (about 2 weeks) for hormonal concentrations to be in a steady state; gradually your body feels better as concentrations regulate the neurohormonal axis

Truly yours

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