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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is positive TPHA normal even after treating syphills?

Answered by
Dr.
Dr. Sandip Kabra

General & Family Physician

Practicing since :2009

Answered : 3078 Questions

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Posted on Mon, 29 Aug 2016 in Infections
Question: I want to know if TPHA will remain positive for life long then what will be side effect of it in future ?
doctor
Answered by Dr. Sandip Kabra 3 hours later
Brief Answer:
Almost no side effect after complete treatment.

Detailed Answer:
Hi
Welcome Health Care Magic

Yes, TPHA test will remain positive throughout life even after complete treatment of syphilis. You should complete the treatment course as directed by your doctor.

VDRL test is used for diagnosis, follow up and response to the treatment of syphilis .

Whereas,TPHA test is used only for diagnosis. It can remain positive even after cured off disease. Titre may change due to some different laboratory techniques.

When your VDRL test will become negative, you are cured of disease.

Negative VDRL is more important and once you will be negative for it,there is almost no side effect life long. Do not worry.

Regards,

Dr.Sandip Kabra
Above answer was peer-reviewed by : Dr. Prasad
doctor
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Follow up: Dr. Sandip Kabra 17 hours later
Ok I have taken already 2 injection as presscribed by Doctor and he suggested 2 more injection. So I would like to know after get these all injection in how many I should go for Blood test ?

And after get negative VDRL but positive TPHA can I get sex without condom with my wife?
doctor
Answered by Dr. Sandip Kabra 1 hour later
Brief Answer:
after 6 months to 1 year.

Detailed Answer:
Hi,
Welcome again,

VDRL test usually comes negative after 6 months to 1 year following successful;l treatment with penicillin (antibiotic) course.

So,I would suggest you to undergo VDRL again after 6 months but remember that your TPHA test will remain positive throughout life.

Once you will have non-reactive (negative) VDRL test,practically your are non-infectious. So you can have sex with your wife even without condom.

Regards,

Dr.Sandip Kabra

Above answer was peer-reviewed by : Dr. Priyanka G Raj
doctor
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