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Is persistent pain in the legs indicative of a pinched nerve?

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Posted on Wed, 22 May 2019
Question: I’m 51 and recently had a positive HLA-B27 blood test. I’m the 8th person in my family (cousins, father) to test positive in the last couple years. 3 of them have Ankylosing Spondylitis.
In October of 2001 I started having constant leg pain. 24/7. It’s my entire leg from upper thigh down to feet. Feels like it’s deep down all the way to the bone. The pain is always in my legs, but also can be widespread throughout my body quite often.
I have trouble standing for periods longer than 7-10 minutes without needing to sit due to pain.
If I over exert myself I need recovery time usually the next day. Knowing this I still try to exercise just not daily. I am going to hurt regardless so might as well, right?? Or maybe not???
I was diagnosed with fibromyalgia in 2002 and Idiopathic Peripheral Neuropathy around 2003 or 2004.
The more time that passes the more I’m questioning the Neuropathy diagnosis. I’ve had 3 nerve conduction studies. 1 came back as PN, next one said not PN and 3rd one was inconclusive if I remember correctly (many years and many different tests ago).
And now with the positive HLA test I wonder if there’s another answer.
I have an appointment with a rheumatologist in April 2018.

Do you have any thoughts?

Oh, I’ve had lower back problems for the last 2 years. Regular chiropractic visits haven’t taken care of it. Had an MRI (lower back) last week-just waiting for results
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Answered by Dr. Sudhir Kumar (52 minutes later)
Brief Answer:

Your symptoms are more likely due to a pinched nerve in the lower back.

Detailed Answer:

Hi,

I agree with you that your symptoms are not related to peripheral neuropathy.

They are more likely due to a pinched nerve in the lower back. MRI of spine (already done) would help confirm the diagnosis.

HLA B27-related ankylosing spondylitis is known to cause severe back pain, however, it does not cause pain radiating from thigh to the leg.

Hope I have answered your query.

Take care

Regards,
Dr Sudhir Kumar, Neurologist
Above answer was peer-reviewed by : Dr. Kampana
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Answered by
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Dr. Sudhir Kumar

Neurologist

Practicing since :1994

Answered : 6205 Questions

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Is persistent pain in the legs indicative of a pinched nerve?

Brief Answer: Your symptoms are more likely due to a pinched nerve in the lower back. Detailed Answer: Hi, I agree with you that your symptoms are not related to peripheral neuropathy. They are more likely due to a pinched nerve in the lower back. MRI of spine (already done) would help confirm the diagnosis. HLA B27-related ankylosing spondylitis is known to cause severe back pain, however, it does not cause pain radiating from thigh to the leg. Hope I have answered your query. Take care Regards, Dr Sudhir Kumar, Neurologist