Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
198 Doctors are Online

Is mental or physical stress a contributory factor to anteroseptal infarct?

User rating for this question
Very Good
Answered by

Cardiologist, Interventional
Practicing since : 1998
Answered : 424 Questions
Can mental stress cause or contribute to an anteroseptal infarct? If so, please explain and please provide citations to any journal articles which support this. Thank you. Can physical stress? What type of mental or physical stress would be required to cause/contribute to anteroseptal infarct?
Posted Thu, 26 Apr 2012 in Hypertension and Heart Disease
Answered by Dr. Prabhakar C Koregol 39 minutes later

Thanks for the query.

Yes, both mental and physical stresses can precipitate a myocardial infarct by being a contributory factor rather than causative.

Multiple explanations’ are sited in literature; most common being increase in adrenaline level which in turn increase blood pressure, heart rate and plaque instability and erosion. But it would be near to impossible to prove or say that it is primarily stress that caused anteroseptal infarct (Myocardial Infarct) or other coronary vessel disease.

"Stress is characterized by an increase in plasma catecholamines and cortisol associated with a rise in heart rate and blood pressure. Plasma epinephrine can increase by a factor of 8 through emotional or physical stress. In contrast, the rise in plasma norepinephrine following physical stress is much higher than that following emotional stress. "
CONCLUSION: A causal relationship between stress and atherosclerosis has not yet been demonstrated in clinical studies. However, there is convincing evidence to accept emotional stress as a potential trigger for the onset of acute myocardial infarction. High physical stress of untrained persons carries an even greater risk for the development of acute myocardial infarction.

Few important references are
1. Gabbay FH, Krantz DS, Kop WJ, et al. Triggers of myocardial ischemia during daily life in patients with coronary artery disease: physical and mental activities, anger and smoking. J Am Coll Cardiol1996;27:585–92.
2. Gullette ECD, Blumenthal JA, Babyak M, et al. Effects of mental stress on myocardial ischemia during daily life. JAMA1997;277:1521–6.
3. Heart 2003;89:475-476 doi:10.1136/heart.89.5.475
Editorial Stress and myocardial infarction

Hope I have given you the information that you were looking for. Do accept the answer if you do not have any further queries. Yet, let me know if I have missed out on any other concerns.

Best wishes

Above answer was peer-reviewed by
Share on Facebook
Share on Twitter
Share on Google+
Question is related to

The user accepted the expert's answer

Ask a Cardiologist

© Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions
Already Rated.
Your rating:

Ask a Doctor