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Is It Safe To Take Xanax Along With Tylenol PM?

Posted on Mon, 7 Sep 2015

Question: Can I take a Xanax with a Tylenol PM?
The Xanax is 0.5 mg
Age is 71 not 77 by the way

Answered by Dr. Vivek Chail (1 hour later)

Brief Answer:
You might take Xanax and Tylenol PM with precautions

Detailed Answer:
Hi XXXXX,
Thanks for writing in to us.

I have read through your query in detail.
Please find my observations below.

1. Xanax contains alprazolam.

2. Tylenol PM contains acetaminophen and diphenhydramine.

3. Alprazolam might interact with diphenhydramine and cause increased dizziness and impaired judgement. You might take Xanax with Tylenol PM and take precautions. Therefore you should not participate in any activity requiring high degree of alertness. Please do not do driving, swimming or put yourself in high risk situation after taking these medicines. Please avoid alcohol after taking these medicines.

Please feel free to correct any oversight in my interpretation of your problems and discuss them in detail as per your requirements.

Hope your query is answered.
Do write back if you have any doubts.

Regards,
Dr.Vivek

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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar