HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

question-icon

Is It Safe To Take Naproxen Or Tylenol Along With Prednisone?

default
Posted on Fri, 19 Sep 2014
Question: I was recently presribed Prednisone. Is it safe to take Naproxen or Tylanol along with Prednisone?
doctor
Answered by Dr. Lohit K (1 hour later)
Brief Answer:
yes. safe. No significant interactions

Detailed Answer:
Hi,

I went through the query and understood your concern.

Yes. The combination is safe with no significant interactions. You can take the drugs in combination. .

I hope this information helps you and answered your concern.
Feel free to ask for any further queries. I will be glad to answer them.

Wish you good health.
Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Lohit K (3 minutes later)
The drug interaction website sais that taking Prednisone w/Naproxen could ruin the lining of the stomach. Is that true??
doctor
Answered by Dr. Lohit K (32 minutes later)
Brief Answer:
side effect. rare for.acute therapy

Detailed Answer:
Hi,

I like to explain the mechanism that happens for better undestanding.

For management of any inflammation, prostaglandin production or its action should be reduced. All NSAIDs like acetaminophen, naproxen, ibuprofen etc. will act by reducing the prostaglandin production which is a protective barrier in stomach. So the chance of gastritis (gastric mucosal damage) is present. Steroids like prednisone will also reduce prostaglandin production. So these drugs act as anti inflammatory agents but can cause side effects.

The side effect can occur with single drug or if not occured with single drug (naproxen) then with combination is rare. More over for acute therapy the side effects are very rare. If you are already suffering from gastritis then take drugs like ranitidine or pantoprazole which will reduce gastric acid secretion and hence there won't be any problem.

I hope this information helps you to know about the side effect you are concerned about. Wish you good health.
Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Lohit K (13 minutes later)
Thanks, Doc! I don't have any gastic issues. So the bottom line is that the side affects of taking Prednisone w/Naproxen is negligible, correct??
doctor
Answered by Dr. Lohit K (19 minutes later)
Brief Answer:
yes. no need to worry much.

Detailed Answer:
Hi,

yes. For side effects it's very difficult to tell which side effects may occur in each individual. We can tell the probable side effects that may occur based on previous experience. Based on my experience I have rarely seen this side effect in normal individual.

So in summary it's a rare side effect and no need to worry much before taking the drug. If you experience any problems then can stop the drug. You can prevent this occurrence by taking gastric acid suppressants.

I hope this helps you to know about the side effects and your concern.

I wish you good health. Feel free to ask for any further queries and I will be glad to answer them.

Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Lohit K (7 minutes later)
I do have some tagamet to reduce stomach acid just in case. Here's my last question: is there any interaction between Prednisone & Duexis Ibupfofen?? Is the anwer the same?
doctor
Answered by Dr. Lohit K (36 minutes later)
Brief Answer:
better in reducing gastritis

Detailed Answer:
Hi

Duexis ibuprofen contain famotidine which acts similar to ranitidine in reducing acid secretion. So the combination is better in preventing the gastritis issue. Rest all the explanation is same.

Hope this answered your query.
Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Lohit K (8 hours later)
Awesome! Thanks, Doc!
doctor
Answered by Dr. Lohit K (2 hours later)
Brief Answer:
wish you good health

Detailed Answer:
Hi,

It's my pleasure. I am happy that the information helped yoy.

If satisfied kindly close the query and write a review as well.

Wish you good health and happy life.
Regards
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
Answered by
Dr.
Dr. Lohit K

General & Family Physician

Practicing since :2007

Answered : 1648 Questions

premium_optimized

The User accepted the expert's answer

Share on

Get personalised answers from verified doctor in minutes across 80+ specialties

159 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
Is It Safe To Take Naproxen Or Tylenol Along With Prednisone?

Brief Answer: yes. safe. No significant interactions Detailed Answer: Hi, I went through the query and understood your concern. Yes. The combination is safe with no significant interactions. You can take the drugs in combination. . I hope this information helps you and answered your concern. Feel free to ask for any further queries. I will be glad to answer them. Wish you good health. Regards