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Is Eating Grapefruit Safe When On Pravastin?

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Posted on Thu, 23 Jan 2014
Question: I am on pravastin. Is it safe to eat grapefruit?
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Answered by Dr. T Shobha Deepak (1 hour later)
Brief Answer: Not recommended to use simultaneously Detailed Answer: Namasthe Welcome to Healthcare-Magic Greetings of the day It is not advisable to take grape juice with pravastin. Grape juice inhibits the enzyme cytochrome P3A4 which is enzyme metabolising pravastin. Concomitant use will lead to elevated level of pravastin causing increased adverse effects including myopathy. In case you require any further assistance, will be glad to assist you. Take care Best Regards Dr T Shobha Deepak MBBS, MD
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Above answer was peer-reviewed by : Dr. Shanthi.E
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Dr. T Shobha Deepak

General & Family Physician

Practicing since :2005

Answered : 1774 Questions

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Is Eating Grapefruit Safe When On Pravastin?

Brief Answer: Not recommended to use simultaneously Detailed Answer: Namasthe Welcome to Healthcare-Magic Greetings of the day It is not advisable to take grape juice with pravastin. Grape juice inhibits the enzyme cytochrome P3A4 which is enzyme metabolising pravastin. Concomitant use will lead to elevated level of pravastin causing increased adverse effects including myopathy. In case you require any further assistance, will be glad to assist you. Take care Best Regards Dr T Shobha Deepak MBBS, MD