Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties

152 Doctors Online
Doctor Image
Dr. Andrew Rynne

Family Physician

Exp 50 years

I will be looking into your question and guiding you through the process. Please write your question below.

Is a first positive for elisa test conclusive?

Answered by
Dr. S. Murugan

HIV AIDS Specialist

Practicing since :1974

Answered : 2766 Questions

Posted on Thu, 21 Aug 2014 in HIV and AIDS
Question: My boyfriend had rotator cuff surgery yesterday, the doctor nicked his finger while operating. they took blood to run routine test and dr just called to say first test for hiv came back positive, the second and third were negative. how likely is it he is infected? He goes in tomorrow to retest.
Answered by Dr. S. Murugan 59 minutes later
Brief Answer:
False positive result can occur though rare.

Detailed Answer:

Welcome to HCM.
Thanks for posting your query.

I can understand your concern about one test positive while the others showed negative.

I would like to know few things:
1. What type of test done for your boy friend. Whether it is a rapid test or ELISA or 4th generation Combo test or PCR TEST?
2.What would be the interval period between these tests?
3. Your boy friend's sexual activities.
These information would help in discussion.
a) Biological false positive or other false positive results were possible with rapid tests, though rare.
b) Certain test antigens are more sensitive and can pick up the antibodies even in lower titre whereas others have a little low sensitivity and show positive after another 15 days or a month.
Anyway the repeat test would be more confirmatory.
Dr S.Murugan
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
Follow up: Dr. S. Murugan 13 hours later
It was an Elisa test. First one positive, subsequent two were negative, all tests from same blood drawn that day. He has had only 3 sexual partners in 35 years.
Answered by Dr. S. Murugan 2 hours later
Brief Answer:
More specific test is necessary to confirm status

Detailed Answer:
Welcome back.

Technical error and labeling error have to be ruled out.
More specific tests like western blot or Antigen based tests like DNA PCR will be able to either confirm or rule out the HIV status.
Dr S.Murugan
Above answer was peer-reviewed by : Dr. Vaishalee Punj

The User accepted the expert's answer

Share on
Question is related to
Diseases and Conditions
Medical Procedures
Lab Tests

Recent questions on  HIV

doctor1 MD

Hi, I am considering having laser hair removal, am HIV+ and currently on medication, but fit and healthy. Is there any reason why I would not be advised to have the procedure? I have not told the clinician of my status nor do I plan to, however are there any risks associated with the procedure or could it have an adverse effect due to the medications?

doctor1 MD

Hi, I went to a Massage center last week and had Oral Sex with the worker over there. She performed annilingus on mine and also Fellatio on me but with food plastic wrap in between her mouth and my penis. I m worried that I got HIV or some other STD s because I m now experiencing minor Aches, pain in fingers of my hand and tingy ness and numbness sometimes. I did in-home Ora quick test and it resulted in negative but still worried as I m in Window period.

doctor1 MD

uhm, Heya... i find it hard to believe i'm doing this, but: I'm an 18 year old male, about 1.90m tall.. today my girlfriend came over and had condoms with her, thinking that we could do something that none of us have done before (if you catch my drift), normaly i have an errection everytime we're kissing and getting a bit "kinky", but when i tried to put the condom on, or even reach for it, my errection just vanished, each time... is it all in my mind or is there something i can do to overcome this shyness problem? (ps. this took me completley by suprise and everything)

doctor1 MD

hi, im 17 and ive had sex before about 3 months ago i had unprotected sex about 2 months later to now i started feeling like pee was stuck in my shaft no matter how many times i pee, it doesnt burn when i pee and i think tthere was white/cream on the top of my penis and both sides of my penis hole get stuck together too, im not sure if i have an std please help?

doctor1 MD

I just had a mutual masturbation session with a sex worker However she removed her hand from inside her vagina and used it roughly on my penis in a hand job Can I get HIV from this means which I was not able to stop after it occurred to me ?

doctor1 MD

i bought food the food was in a container with a plastic at the top covering the container how ever i notice the plastic on 1 container was slightly open on a container with food inside any RISK for hiv hep b,c

doctor1 MD

Dear doctor thanks for your valuable reply however my further query is for last two weeks I have a mild rash under my eye which is persistent and is not going away...I had read somewhere in the webmd website that facial rashes are the first sign...