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Is Tylenol Safe To Take While On Metformin?

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Posted on Wed, 19 Oct 2016
Question: My lady takes Metformin and Atenolol and her doctor said that it was okay to take Tylenol for pain. Is it okay to take Tylenol PM instead of just Tylenoll?
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Answered by Dr. Noble Zachariah (13 minutes later)
Brief Answer:
Yes but beware of the sedation

Detailed Answer:
Hello,
Welcome and thanks for your query.
There is no adverse interaction between Metformin, Atenolol and Tylenol PM.
Tylenol PM contains a sedating antihistamine Diphenhydramine in addition to Tylenol and this may make her sleepy.
So take care of that and she should do anything that can cause harm to herself or others because of the sedation that may be present.
Do get back to me if you have further queries.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Noble Zachariah

Internal Medicine Specialist

Practicing since :1974

Answered : 2319 Questions

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Is Tylenol Safe To Take While On Metformin?

Brief Answer: Yes but beware of the sedation Detailed Answer: Hello, Welcome and thanks for your query. There is no adverse interaction between Metformin, Atenolol and Tylenol PM. Tylenol PM contains a sedating antihistamine Diphenhydramine in addition to Tylenol and this may make her sleepy. So take care of that and she should do anything that can cause harm to herself or others because of the sedation that may be present. Do get back to me if you have further queries.