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Dr. Andrew Rynne

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Is OGTT better than Hba1c test to diagnose prediabetes or diabetes?

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Dr. Mirjeta Guni

Endocrinologist

Practicing since :2006

Answered : 1996 Questions

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Posted on Wed, 9 May 2018 in Diabetes
Question: Hi,
I have been asked to take more detailed tests for diabetes or pre-diabetes. My current plasma glucose level is 5.0 fasting.

Is an oral glucose tolerance test more accurate or would lead to a better idea of my condition than the HbA1c test?


Thankyou.
doctor
Answered by Dr. Mirjeta Guni 1 hour later
Brief Answer:
Best test to diagnose Diabetes:

Detailed Answer:
Hello and thank you for asking!
Your question is very interesting. Today there are many studies that intend to compare the sensitivity of type 2 Diabetes diagnosis tests and Hba1c results more sensitive than fasting plasma glucose and OGTT.
So i would recommend to check HbA1c rather than preform OGTT.
Here is a large study confirming it.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC0000/

Best wishes,
Dr.Mirjeta


Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
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Follow up: Dr. Mirjeta Guni 1 hour later
Thanks Dr. Mirjeta,

I will consider asking for this test. Thanks for the link. I have read it briefly. Is it correct to say that the HbA1c test is still only roughly 70% accurate or will only pick up diabetes in 70% of patients who have the condition?


Thankyou.
doctor
Answered by Dr. Mirjeta Guni 43 minutes later
Brief Answer:
About HbA1c sensitivity:

Detailed Answer:
Welcome back!
It means that it is 70% accurate if used alone to diagnose DIabetes, of course together with fasting and postprandial glucose checks, the sensitivity increases.
Best wishes,
Dr.Mirjeta
Above answer was peer-reviewed by : Dr. Prasad
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