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Is Acyclovir Advisable After Taking Azithromycin?

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Posted on Tue, 6 Dec 2016
Question: I have just finished a Z-pak--and know the zithromycin stays active in my system for many days. Can I take acyclovir now for an outbreak?
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Answered by Dr. Scott Rebich (1 hour later)
Brief Answer:
You can take acyclovir and azithromycin together

Detailed Answer:
Hi there,

Azithromycin can last in your system for 5 days after the last dose. Therefore, if you take a 5 day course, the antibiotic will be good for 10 days total.

There is no interaction with acyclovir and therefore you can take acyclovir while on azithromycin. You should not experience any issues.

Let me know if you have additional questions.
Note: For further follow up on related General & Family Physician Click here.
Above answer was peer-reviewed by : Dr. Raju A.T
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Answered by
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Dr. Scott Rebich

Internal Medicine Specialist

Practicing since :2015

Answered : 283 Questions

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Is Acyclovir Advisable After Taking Azithromycin?

Brief Answer: You can take acyclovir and azithromycin together Detailed Answer: Hi there, Azithromycin can last in your system for 5 days after the last dose. Therefore, if you take a 5 day course, the antibiotic will be good for 10 days total. There is no interaction with acyclovir and therefore you can take acyclovir while on azithromycin. You should not experience any issues. Let me know if you have additional questions.