Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties

138 Doctors Online
Doctor Image
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

I will be looking into your question and guiding you through the process. Please write your question below.

Is 4th generation HIV test result conclusive 28 days after exposure?

Answered by
Dr.
Dr. Sunil Jangid

HIV AIDS Specialist

Practicing since :2009

Answered : 1907 Questions

default
Posted on Mon, 5 Mar 2018 in HIV and AIDS
Question: Hello specialists. Had my 4th gen test today (28th day after exposure) and it came out negative!

Just a few more questions if you dont mind, do i have to retest after this or are my results conclusive?
doctor
Answered by Dr. Sunil Jangid 39 minutes later
Brief Answer:
You need to get tested after 3 months.

Detailed Answer:
Dear XXXX,

Welcome to HCM.

The window period for HIV varies from 15 days to 3 months so as per protocol you need to get tested after 3 months to get 100% conclusive result but first you need to tell me in detail about your exposure so that I can explain you in much better way about the risk.

As such negative 4th generation test after 28 days of exposure is considered around 95% accurate and reliable so you need not to get worried or tensed for HIV. Be relaxed and get back to me with all the details about the incidence. I am here to help you out always.

Thank You
Above answer was peer-reviewed by : Dr. Nagamani Ng
doctor
default
Follow up: Dr. Sunil Jangid 7 minutes later
Hello doctor. My exposure was a massage which ended with a hand job

My main worry was that my leg got in contact with the girl's vaginal area (she was in her underwear) the reason i tested is that i was mostly afraid of vaginal fluids getting in contact with some cuts i had at that point of time. cuts were reddish around the edges but not bleeding
doctor
Answered by Dr. Sunil Jangid 10 minutes later
Brief Answer:
The risk is very unlikely.

Detailed Answer:
Dear XXXX,

Welcome back and thanks for follow-up.

HIV virus can enter into the body through cuts or abrasions but the chances of HIV infection through the way you had mentioned is very unlikely even if your partner was HIV positive so don't get afraid or feared. The risk of infection through hand job is not there so forget about the episode and live your life normally. For any further help you can write to me again and I will help you straight way.

Thank You
Above answer was peer-reviewed by : Dr. Nagamani Ng
doctor
default
Follow up: Dr. Sunil Jangid 1 hour later
So doctor, my 4th gen test that i took is conclusive? do i have to retest at 3 months post exposure.

As always, im just afraid of the what ifs, if you know what i mean
doctor
Answered by Dr. Sunil Jangid 3 hours later
Brief Answer:
It is 95% conclusive.

Detailed Answer:
Dear XXXX,

Welcome back once again.

Your 4th generation test result is 95% conclusive but to get 100% conclusive result you need to get tested again after 3 months as per international HIV guidelines. Allay the fear or anxiety related to HIV as the possibility of positive result after 3 months is practically nil. Be relaxed, close this chapter and move on in life.

Thank You
Above answer was peer-reviewed by : Dr. Nagamani Ng
doctor
default
Follow up: Dr. Sunil Jangid 37 hours later
Does this mean that i can live my live as per normal withoud any fear? cause the statistics are high?

Also doc, can hiv spread from human to object (panties) and to another human?
doctor
Answered by Dr. Sunil Jangid 52 minutes later
Brief Answer:
Yes you can.

Detailed Answer:
Dear XXXX,

You can definitely live your life as normal without any fear or tension and the spread of HIV through object to human such as panties is not practicle so avoid thinking on that, forget about the incidence and move on. Wishing you very happy and healthy life ahead.

Thank You
Above answer was peer-reviewed by : Dr. Yogesh D
doctor
default
Follow up: Dr. Sunil Jangid 2 days later
Hello doc. Sorry just a question since ive had my 4th gen done at 4 weeks?

What does the test actually test for? And is there any instance where the test has failed?
doctor
Answered by Dr. Sunil Jangid 23 minutes later
Brief Answer:
It tests for both antigen and antibody.

Detailed Answer:
Dear XXXX,

Welcome to HCM once again.

4th generation HIV Duos test detects for both HIV antigen as well as antibody and it is considered as 95% reliable after 4 weeks so don't be afraid about the accuracy of test and move on in life as you are absolutely safe and risk free.

Thank You
Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
default
Follow up: Dr. Sunil Jangid 14 minutes later
I tested on the 28th day itself. its still 95% right?

Thanks for all your replies doctor
doctor
Answered by Dr. Sunil Jangid 22 minutes later
Brief Answer:
Yes after 28 days it is 95% accurate.

Detailed Answer:
Dear XXXX,

Welcome back and thanks for follow-up.

The test result for HIV Duos is 95% accurate after 28 days so you need not to worry at all. Be relaxed, forget about the episode and move on happily.

Thank You
Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
default
Follow up: Dr. Sunil Jangid 2 hours later
Hope you dont mind me asking for more info doc.


The p24 antigens, can you give me details about the protein? Ive read alot but cant seem to get info about it. The antigen is present because of infection right? And ive read that it peaks at the 28th day. Is that one of the reasons why im considered uninfected? Because the test coudnt detect the antigents?

Also, is there such thing as undetectable antigens?
doctor
Answered by Dr. Sunil Jangid 17 hours later
Brief Answer:
There is nothing like undetectable antigens.

Detailed Answer:
Dear XXXX,

Welcome back and thanks for follow-up.

P24 is protein antigen that is present on outer surface of the virus and if the person is infected with HIV then 4th generation HIV Duos test will definitely detect the presence of the antigen because it is nothing like any undetectable antigen in infected individual so don't get worried and stop thinking too much about HIV as you are safe and risk free.

Thank You
Above answer was peer-reviewed by : Dr. Kampana
doctor
premium_optimized

The User accepted the expert's answer

Share on
Question is related to
Diseases and Conditions ,  

Recent questions on  Anxiety

doctor1 MD

hi docter, my head, neck, hands, back and legs are itching all the time. Basically all over. have trouble sleeping lately like anxiety heart beats fast.. WHAT CAN THIS BE WORRIED. I was diagnosed with non hodgkins lymphoma 10 years ago. Do you think it has something to do with that?

doctor1 MD

Hello.. I am a 35 year old female and I have been noticing my heart is skipping every 5th to 8th beat. This is something that started all of a sudden. I do suffer from anxiety disorder and I do take medications daily for this. I drink plenty of water and exercise. I also drink at least 1 cup of coffee per day. I recently was put on a 24 hour holter monitor and the recording did show some palpitations. Since I had the monitor this has been occurring through the entire day. They don t stop. What should I do from here?

doctor1 MD

I started taking aspiren regimen 3 days ago without asking my doctor I have rapid heart beat and heart palpatations and anxiety disorder. I thought it would help, I felt better for last three days no rapid heartbeat as bad as it usually is but got severe headaches. Should I continue taking it today, also I thought it would be good for arthritis in my lower back, but the headaches terrible. My blood pressure has been low for the last month 110 over 78 and since taking the regimen it has gone up to 120 to 130 I think that s a better blood pressure

doctor1 MD

Hello ! I am a 38 year old female. I have been having really bad dizziness for almost 12 years now. It started with a vertigo attack out of the blue in 2000 . I had not been sick prior to this and was in good health. After the vertigo attack I was left with a rocking sensation and general off balanced feeling.This was all day every day to some degree. Smetimes it was bad and sometimes I could handle it. I would lay in bed at night and feel like I was on a ship out at sea. The doctors thought it was anxiety but I knew my body and knew this was not from anxiety. I had many blood tests for diabetes , thyroid, anemia and others to check for deficiencies and many others. I had ultra sounds of my heart, ekg s, blood test s to check heart enzymes , liver function and kidney function. I had an EEG also. All of these tests came back normal. I had a c-scan of my head and neck and also a MRI. They did find a small meningioma tumor in the right front lobe of my brain but said that it was benign and was not anything to worry about. I then saw a neurologist who said he didn t think it was brain related. I then went to an ENT and had the ENG and other test done. He determined I had menieres disease due to symptoms and an abnormal caloric test. I started vestibular rehab and felt better after a while. I still had dizziness everyday all day but it was much more bearable and I got on with life again. The last eight months symptoms have came crashing back really bad again. It started with me being really tired and way dizzier then normal. I was under a tremendous amount of pressure at work and just every day life. When it got really bad I was driving home from a restaurant with my kids. We had just went out to eat and it was Asian food, which I know is packed with sodium and causes issues with people with menieres disease. Anyway, I was driving back and started feeling really tired and kept yawning. I then felt really bloated and like my jeans were too tight. So I felt like I couldn t breathe well and kept yawning over and over. I then started feeling like I may pass out. I stopped at the red light and put my car in park just in case I did. Well it passed after a minute so I continued home which was only a few blocks away. When I got out of the car I felt really shaky and weak and just wanted to lay down. My mom checked my sugar levels and it was a little high, like 180. SO I layed down and thought it was the food, For the next few weeks I felt really tired and still dizzy but not the passing out feeling. Then one night at work a really overwhelming tired feeling came over me and I fet like I was going to pass out again. They called the emergency department and they transported me to the hospital. I hadn t ate much that day and they thought it was because of that because all of the blood tests, ekg, and chest x-rays came back normal. I kept being really tired and dizzy and I finally had to quit work and even give up driving because every time I drove I would feel dizzy and weak. I went back to the ENT and he redid the ENG and everything came back normal this time.He said he thinks I still have menieres but isn t sure if that is what it is since testing was normal this time. I had another MRI, which was no different then the last one. I am just not sure where to go from here and I don t really think my doctors know either and are chalking it up to anxiety. I know that I do have anxiety but it is caused by the way I feel. Any advice or suggestions would be appreciated. Medicines - Lotrel for HBP - controlled on medicine. Have been on for years. Atenolol foe heart palpitations- works wonderfully - have been on for years also Symptoms Dizziness -Whirling in head- sometimes quick vertigo lasting a few seconds- feeling as though on an elevator when it stops - Foggy headed - sometimes can t concentrate due to head symptoms Weakness Fatigued Eyes feel blurred sometimes or hard to focus Walking makes dizziness worse / laying down brings relief / when standing still in one place I feel like I may fall over Head pressure and ear pressure Ringing in ears at times Sorry this is so long but I wanted to give as much information as possible. Thank you in advance.

doctor1 MD

Hi. I am a bit concerned about the dose of lorazepam that i take. 1mg split in 0.5 morning and evening. It's been 1 month since i started this treatment, along with 10 mg of Cipralex . My psychiatrist said to stay another month on lorazepam due to...

doctor1 MD

I have fluttering in My upper stomach while sitting. Don't notice while standing. It appears worse when I breath out. Does not hurt just flutters

doctor1 MD

I just got a recall back from a mammogram app. I'm very scared, what could it be if not cancer?